A Potent Far-Upstream Enhancer in the Mouse Proα2(I) Collagen Gene Regulates Expression of Reporter Genes in Transgenic Mice

We have identified three DNase I-hypersensitive sites in chromatin between 15 and 17 kb upstream of the mouse proα2(I) collagen gene. These sites were detected in cells that produce type I collagen but not in cells that do not express these genes. A construction containing the sequences from -17 kb...

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Veröffentlicht in:	The Journal of cell biology 1996-09, Vol.134 (5), p.1333-1344
Hauptverfasser:	Bou-Gharios, George, Garrett, Lee Ann, Rossert, Jerome, Niederreither, Karen, Eberspaecher, Heidi, Smith, Chad, Black, Carol, de Crombrugghe, Benoit
Format:	Artikel
Sprache:	eng
Schlagworte:	Bones Cell lines Cells Collagens Embryos Fibroblasts Osteoblasts Reporter genes Transgenes Transgenic animals
Online-Zugang:	Volltext
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