Mitochondrial DNA polymorphisms in Carib people of Belize
Analysis of mitochondrial DNA (mtDNA) control region polymorphisms in 28 Carib people of Belize, former British Honduras, revealed high levels of genetic admixture with West African populations. A previously characterized length mutation consisting of a deletion of nine base pairs in an intergenic m...
Gespeichert in:
| Veröffentlicht in: | Proceedings of the Royal Society. B, Biological sciences Biological sciences, 1997-08, Vol.264 (1385), p.1217-1224 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1224 |
|---|---|
| container_issue | 1385 |
| container_start_page | 1217 |
| container_title | Proceedings of the Royal Society. B, Biological sciences |
| container_volume | 264 |
| creator | Monsalve, M. V. Hagelberg, E. |
| description | Analysis of mitochondrial DNA (mtDNA) control region polymorphisms in 28 Carib people of Belize, former British Honduras, revealed high levels of genetic admixture with West African populations. A previously characterized length mutation consisting of a deletion of nine base pairs in an intergenic mtDNA region was observed in two of the individuals. Phylogenetic analysis of mtDNA control region sequences associated with the mutation suggested that it arose independently in different geographical locations. Whereas in one individual the deletion reflects the Amerindian ancestry of the Caribs, in the second case it seems to be of African origin, as it occurred in conjunction with an mtDNA type found in sub-Saharan Africa. Our results agree with historical accounts on the origins of the Caribs of Belize. |
| doi_str_mv | 10.1098/rspb.1997.0168 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_istex</sourceid><recordid>TN_cdi_istex_primary_ark_67375_V84_V37BCR29_J</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>50874</jstor_id><sourcerecordid>50874</sourcerecordid><originalsourceid>FETCH-LOGICAL-c694t-2722fbdad1edc0dcc1c9e5b954fc3459350fb768921f85c93b938b0cc6488153</originalsourceid><addsrcrecordid>eNp9Ustu1DAUjRCoDIUtCySkrNhl8COO7Q2iM7xVHipVt1eJ4zQekjjYSWH69TiT0YgRoivLOo977rGj6ClGS4ykeOl8XyyxlHyJcCbuRQuccpwQydL70QLJjCQiZeRh9Mj7DUJIMsFOohNJkcAyXUTysxmsqm1XOpM38ZsvZ3Fvm21rXV8b3_rYdPE6d6aIe237Rse2ile6Mbf6cfSgyhuvn-zP0-jy3dvL9Yfk_Ov7j-uz80RlMh0SwgmpijIvsS4VKpXCSmpWhHyVoimTlKGq4JmQBFeCKUkLSUWBlMpSITCjp9Gr2bYfizZY6G5weQO9M23utmBzA8dIZ2q4tjcQ2hAsk8Hgxd7A2Z-j9gO0xivdNHmn7eiBSyIl41kgLmeictZ7p6vDEIxg6hqmrmHqGqaug-D539EO9H25Aacz7uw2NGSV0cMWNnZ0Xbj-39Xfpbr4_m0VyOiGZKnBVDBAgmLEsWAMbk2_s5sIEAhgvB817GjHY_6d-myeuvGDdYdVGBJ8WiSZQeMH_fsA5u4HZJxyBlcihSvKV-sLIuFT4JOZX5vr-pdxGo52CZfe-WIXcBcNE8yD6PWdoimvst0QnvlYCdXYhA9RVvQPaE3yrw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79299576</pqid></control><display><type>article</type><title>Mitochondrial DNA polymorphisms in Carib people of Belize</title><source>MEDLINE</source><source>Jstor Complete Legacy</source><source>PubMed Central</source><creator>Monsalve, M. V. ; Hagelberg, E.</creator><creatorcontrib>Monsalve, M. V. ; Hagelberg, E.</creatorcontrib><description>Analysis of mitochondrial DNA (mtDNA) control region polymorphisms in 28 Carib people of Belize, former British Honduras, revealed high levels of genetic admixture with West African populations. A previously characterized length mutation consisting of a deletion of nine base pairs in an intergenic mtDNA region was observed in two of the individuals. Phylogenetic analysis of mtDNA control region sequences associated with the mutation suggested that it arose independently in different geographical locations. Whereas in one individual the deletion reflects the Amerindian ancestry of the Caribs, in the second case it seems to be of African origin, as it occurred in conjunction with an mtDNA type found in sub-Saharan Africa. Our results agree with historical accounts on the origins of the Caribs of Belize.</description><identifier>ISSN: 0962-8452</identifier><identifier>EISSN: 1471-2954</identifier><identifier>DOI: 10.1098/rspb.1997.0168</identifier><identifier>PMID: 9308194</identifier><language>eng</language><publisher>England: The Royal Society</publisher><subject>Africa South of the Sahara - ethnology ; African Continental Ancestry Group - genetics ; Base Sequence ; Belize ; DNA ; DNA Primers - genetics ; DNA, Mitochondrial - genetics ; Emigration and Immigration ; Ethnic Groups - genetics ; Evolution ; Evolutionary genetics ; Female ; Genetics, Population ; Haplotypes ; Human genetics ; Humans ; Indians, Central American - genetics ; Male ; Mitochondrial DNA ; Molecular Sequence Data ; Polymerase Chain Reaction ; Polymorphism, Genetic ; Population genetics ; Sequencing</subject><ispartof>Proceedings of the Royal Society. B, Biological sciences, 1997-08, Vol.264 (1385), p.1217-1224</ispartof><rights>Copyright 1997 The Royal Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c694t-2722fbdad1edc0dcc1c9e5b954fc3459350fb768921f85c93b938b0cc6488153</citedby><cites>FETCH-LOGICAL-c694t-2722fbdad1edc0dcc1c9e5b954fc3459350fb768921f85c93b938b0cc6488153</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/50874$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/50874$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,725,778,782,801,883,27907,27908,53774,53776,58000,58233</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9308194$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Monsalve, M. V.</creatorcontrib><creatorcontrib>Hagelberg, E.</creatorcontrib><title>Mitochondrial DNA polymorphisms in Carib people of Belize</title><title>Proceedings of the Royal Society. B, Biological sciences</title><addtitle>Proc Biol Sci</addtitle><description>Analysis of mitochondrial DNA (mtDNA) control region polymorphisms in 28 Carib people of Belize, former British Honduras, revealed high levels of genetic admixture with West African populations. A previously characterized length mutation consisting of a deletion of nine base pairs in an intergenic mtDNA region was observed in two of the individuals. Phylogenetic analysis of mtDNA control region sequences associated with the mutation suggested that it arose independently in different geographical locations. Whereas in one individual the deletion reflects the Amerindian ancestry of the Caribs, in the second case it seems to be of African origin, as it occurred in conjunction with an mtDNA type found in sub-Saharan Africa. Our results agree with historical accounts on the origins of the Caribs of Belize.</description><subject>Africa South of the Sahara - ethnology</subject><subject>African Continental Ancestry Group - genetics</subject><subject>Base Sequence</subject><subject>Belize</subject><subject>DNA</subject><subject>DNA Primers - genetics</subject><subject>DNA, Mitochondrial - genetics</subject><subject>Emigration and Immigration</subject><subject>Ethnic Groups - genetics</subject><subject>Evolution</subject><subject>Evolutionary genetics</subject><subject>Female</subject><subject>Genetics, Population</subject><subject>Haplotypes</subject><subject>Human genetics</subject><subject>Humans</subject><subject>Indians, Central American - genetics</subject><subject>Male</subject><subject>Mitochondrial DNA</subject><subject>Molecular Sequence Data</subject><subject>Polymerase Chain Reaction</subject><subject>Polymorphism, Genetic</subject><subject>Population genetics</subject><subject>Sequencing</subject><issn>0962-8452</issn><issn>1471-2954</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9Ustu1DAUjRCoDIUtCySkrNhl8COO7Q2iM7xVHipVt1eJ4zQekjjYSWH69TiT0YgRoivLOo977rGj6ClGS4ykeOl8XyyxlHyJcCbuRQuccpwQydL70QLJjCQiZeRh9Mj7DUJIMsFOohNJkcAyXUTysxmsqm1XOpM38ZsvZ3Fvm21rXV8b3_rYdPE6d6aIe237Rse2ile6Mbf6cfSgyhuvn-zP0-jy3dvL9Yfk_Ov7j-uz80RlMh0SwgmpijIvsS4VKpXCSmpWhHyVoimTlKGq4JmQBFeCKUkLSUWBlMpSITCjp9Gr2bYfizZY6G5weQO9M23utmBzA8dIZ2q4tjcQ2hAsk8Hgxd7A2Z-j9gO0xivdNHmn7eiBSyIl41kgLmeictZ7p6vDEIxg6hqmrmHqGqaug-D539EO9H25Aacz7uw2NGSV0cMWNnZ0Xbj-39Xfpbr4_m0VyOiGZKnBVDBAgmLEsWAMbk2_s5sIEAhgvB817GjHY_6d-myeuvGDdYdVGBJ8WiSZQeMH_fsA5u4HZJxyBlcihSvKV-sLIuFT4JOZX5vr-pdxGo52CZfe-WIXcBcNE8yD6PWdoimvst0QnvlYCdXYhA9RVvQPaE3yrw</recordid><startdate>19970822</startdate><enddate>19970822</enddate><creator>Monsalve, M. V.</creator><creator>Hagelberg, E.</creator><general>The Royal Society</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19970822</creationdate><title>Mitochondrial DNA polymorphisms in Carib people of Belize</title><author>Monsalve, M. V. ; Hagelberg, E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c694t-2722fbdad1edc0dcc1c9e5b954fc3459350fb768921f85c93b938b0cc6488153</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Africa South of the Sahara - ethnology</topic><topic>African Continental Ancestry Group - genetics</topic><topic>Base Sequence</topic><topic>Belize</topic><topic>DNA</topic><topic>DNA Primers - genetics</topic><topic>DNA, Mitochondrial - genetics</topic><topic>Emigration and Immigration</topic><topic>Ethnic Groups - genetics</topic><topic>Evolution</topic><topic>Evolutionary genetics</topic><topic>Female</topic><topic>Genetics, Population</topic><topic>Haplotypes</topic><topic>Human genetics</topic><topic>Humans</topic><topic>Indians, Central American - genetics</topic><topic>Male</topic><topic>Mitochondrial DNA</topic><topic>Molecular Sequence Data</topic><topic>Polymerase Chain Reaction</topic><topic>Polymorphism, Genetic</topic><topic>Population genetics</topic><topic>Sequencing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Monsalve, M. V.</creatorcontrib><creatorcontrib>Hagelberg, E.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Proceedings of the Royal Society. B, Biological sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Monsalve, M. V.</au><au>Hagelberg, E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mitochondrial DNA polymorphisms in Carib people of Belize</atitle><jtitle>Proceedings of the Royal Society. B, Biological sciences</jtitle><addtitle>Proc Biol Sci</addtitle><date>1997-08-22</date><risdate>1997</risdate><volume>264</volume><issue>1385</issue><spage>1217</spage><epage>1224</epage><pages>1217-1224</pages><issn>0962-8452</issn><eissn>1471-2954</eissn><abstract>Analysis of mitochondrial DNA (mtDNA) control region polymorphisms in 28 Carib people of Belize, former British Honduras, revealed high levels of genetic admixture with West African populations. A previously characterized length mutation consisting of a deletion of nine base pairs in an intergenic mtDNA region was observed in two of the individuals. Phylogenetic analysis of mtDNA control region sequences associated with the mutation suggested that it arose independently in different geographical locations. Whereas in one individual the deletion reflects the Amerindian ancestry of the Caribs, in the second case it seems to be of African origin, as it occurred in conjunction with an mtDNA type found in sub-Saharan Africa. Our results agree with historical accounts on the origins of the Caribs of Belize.</abstract><cop>England</cop><pub>The Royal Society</pub><pmid>9308194</pmid><doi>10.1098/rspb.1997.0168</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0962-8452 |
| ispartof | Proceedings of the Royal Society. B, Biological sciences, 1997-08, Vol.264 (1385), p.1217-1224 |
| issn | 0962-8452 1471-2954 |
| language | eng |
| recordid | cdi_istex_primary_ark_67375_V84_V37BCR29_J |
| source | MEDLINE; Jstor Complete Legacy; PubMed Central |
| subjects | Africa South of the Sahara - ethnology African Continental Ancestry Group - genetics Base Sequence Belize DNA DNA Primers - genetics DNA, Mitochondrial - genetics Emigration and Immigration Ethnic Groups - genetics Evolution Evolutionary genetics Female Genetics, Population Haplotypes Human genetics Humans Indians, Central American - genetics Male Mitochondrial DNA Molecular Sequence Data Polymerase Chain Reaction Polymorphism, Genetic Population genetics Sequencing |
| title | Mitochondrial DNA polymorphisms in Carib people of Belize |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T09%3A00%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_istex&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Mitochondrial%20DNA%20polymorphisms%20in%20Carib%20people%20of%20Belize&rft.jtitle=Proceedings%20of%20the%20Royal%20Society.%20B,%20Biological%20sciences&rft.au=Monsalve,%20M.%20V.&rft.date=1997-08-22&rft.volume=264&rft.issue=1385&rft.spage=1217&rft.epage=1224&rft.pages=1217-1224&rft.issn=0962-8452&rft.eissn=1471-2954&rft_id=info:doi/10.1098/rspb.1997.0168&rft_dat=%3Cjstor_istex%3E50874%3C/jstor_istex%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79299576&rft_id=info:pmid/9308194&rft_jstor_id=50874&rfr_iscdi=true |