Synthetic Studies toward the Partial Ergot Alkaloid LY228729, a Potent 5HT1A Receptor Agonist

Synthetic studies on LY228729 (3) afforded two innovative approaches for the construction of this class of partial ergoline 5HT1a receptor agonists. The first synthesis is based upon a diastereoselective epoxidation of racemic olefin 5, followed by ring opening and covalent resolution to furnish the...

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Veröffentlicht in:	Journal of organic chemistry 1997-12, Vol.62 (25), p.8640-8653
Hauptverfasser:	Carr, M. A, Creviston, P. E, Hutchison, D. R, Kennedy, J. H, Khau, V. V, Kress, T. J, Leanna, M. R, Marshall, J. D, Martinelli, M. J, Peterson, B. C, Varie, D. L, Wepsiec, J. P
Format:	Artikel
Sprache:	eng
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