Exothermic Effects Observed upon Heating of β2-Microglobulin Monomers in the Presence of Amyloid Seeds
To understand the initial stages in the formation of amyloid fibrils of β2-microglobulin, a protein responsible for dialysis-related amyloidosis, the effects of heat on the acid-unfolded monomer at pH 2.5 were studied. In the presence of a low concentration of seed fibrils, differential scanning cal...
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Veröffentlicht in: | Biochemistry (Easton) 2006-07, Vol.45 (29), p.8760-8769 |
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Format: | Artikel |
Sprache: | eng |
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