Exothermic Effects Observed upon Heating of β2-Microglobulin Monomers in the Presence of Amyloid Seeds

To understand the initial stages in the formation of amyloid fibrils of β2-microglobulin, a protein responsible for dialysis-related amyloidosis, the effects of heat on the acid-unfolded monomer at pH 2.5 were studied. In the presence of a low concentration of seed fibrils, differential scanning cal...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biochemistry (Easton) 2006-07, Vol.45 (29), p.8760-8769
Hauptverfasser: Sasahara, Kenji, Naiki, Hironobu, Goto, Yuji
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!