Propensity for Helix Formation in the Hydrophobic Peptides K2(LA) x (x = 6, 8, 10, 12) in Monolayer, Bulk, and Lipid-Containing Phases. Infrared and Circular Dichroism Studies

A series of hydrophobic peptides K2(LA) x (x = 6, 8, 10, 12) has been synthesized. IR and CD studies in MeOH solution are reported, along with IR studies of these species in vesicles with 1,2-dipalmitoylphosphatidylcholine, and IR Reflection−Absorption Spectroscopy (IRRAS) studies of peptide and lip...

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Veröffentlicht in:Journal of the American Chemical Society 1998-02, Vol.120 (4), p.792-799
Hauptverfasser: Dieudonné, Darline, Gericke, Arne, Flach, Carol R, Jiang, Xin, Farid, Ramy S, Mendelsohn, Richard
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Sprache:eng
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