Mechanism of Peroxynitrite Interaction with Ferric Hemoglobin and Identification of Nitrated Tyrosine Residues. CO2 Inhibits Heme-Catalyzed Scavenging and Isomerization

Hemoproteins are one of the major targets of peroxynitrite in vivo. It has been proposed that the bimolecular heme/peroxynitrite interaction results in both peroxynitrite inactivation (scavenging) and catalysis of tyrosine nitration. In this study, we used spectroscopic techniques to analyze the rea...

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Veröffentlicht in:	Biochemistry (Easton) 2001-12, Vol.40 (50), p.15300-15309
Hauptverfasser:	Pietraforte, Donatella, Salzano, Anna Maria, Scorza, Giuseppe, Marino, Gennaro, Minetti, Maurizio
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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