Preclinical Toxicology Studies with Nizatidine, A New H2-Receptor Antagonist: Acute, Subchronic, and Chronic Toxicity Evaluations
Nizatidine (NIZ), a new antiulcer drug, was evaluated for toxicity in acute, subchronic, and chronic tests. Acute toxicity studies were conducted in rats, mice, dogs, and monkeys. Median lethal doses (MLD) in rodents were greater than 1600,230, and 1000 mg/kg by oral (po), iv, and sc administration,...
Gespeichert in:
Veröffentlicht in: | Toxicological sciences 1989-11, Vol.13 (4), p.778-792 |
---|---|
Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Schreiben Sie den ersten Kommentar!