Roles of the Ser146, Tyr159, and Lys163 Residues in the Catalytic Action of 7α-Hydroxysteroid Dehydrogenase from Escherichia coli

The Escherichia coli 7α-hydroxysteroid dehydrogenase (7α-HSDH; EC 1.1.1.159) has been the subject of our studies, including the cloning of its gene, and determination of the crystal structures of its binary and ternary complexes [J. Bacteriol 173, 2173–2179 (1991); Biochemistry 35, 7715–7730 (1996)]...

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Veröffentlicht in:	Journal of biochemistry (Tokyo) 1998-09, Vol.124 (3), p.634-641
Hauptverfasser:	Tanabe, Tetsurou, Tanaka, Nobutaka, Uchikawa, Kouichiro, Kabashima, Tsutomu, Ito, Kiyoshi, Nonaka, Takamasa, Mitsui, Yukio, Tsuru, Masato, Yoshimoto, Tadashi
Format:	Artikel
Sprache:	eng
Schlagworte:	catalytic mechanism site-directed mutagenesis steroid dehydrogenase X-ray analysis
Online-Zugang:	Volltext
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