Role of cytochrome P1 in the induction of NAD(P)H:quinone reductase in a murine hepatoma cell line and its mutants

NAD(P)H:Quinone oxidoreductase (QR) is a widely-distributed enzyme that promotes obligatory two-electron reductions of quinones and thereby protects cells against the cytotoxicity of quinones and their metabolic precursors. QR is induced by a wide variety of chemoprotectors in many animal tissues as...

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Veröffentlicht in:	Carcinogenesis (New York) 1987-10, Vol.8 (10), p.1549-1553
Hauptverfasser:	De Long, Mary J., Santamaria, Annette B., Talalay, Paul
Format:	Artikel
Sprache:	eng ; jpn
Online-Zugang:	Volltext
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