A variance-stabilizing transformation for gene-expressionmicroarray data

Motivation: Standard statistical techniques often assume that data are normally distributed, with constant variance not depending on the mean of the data. Data that violate these assumptions can often be brought in line with the assumptions by application of a transformation. Gene-expression microar...

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Veröffentlicht in:Bioinformatics 2002-07, Vol.18 (suppl-1), p.S105-S110
Hauptverfasser: Durbin, B.P., Hardin, J.S., Hawkins, D.M., Rocke, D.M.
Format: Artikel
Sprache:eng ; jpn
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