New diagnostic criteria for infective endocarditis
Objective The purpose of this study was to determine the sensitivity and specificity of new criteria proposed by Duke University for case definition of infective endocarditis as compared to the previously accepted Von Reyn criteria. Patients A total of 143 consecutive suspected cases of infective en...
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| Veröffentlicht in: | European heart journal 1997-07, Vol.18 (7), p.1149-1156 |
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| container_title | European heart journal |
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| creator | Cecchi, E. Parrini, I. Chinaglia, A. Pomari, F. Brusasco, G. Bobbio, M. Trinchero, R. Brusca, A. |
| description | Objective The purpose of this study was to determine the sensitivity and specificity of new criteria proposed by Duke University for case definition of infective endocarditis as compared to the previously accepted Von Reyn criteria. Patients A total of 143 consecutive suspected cases of infective endocarditis in 137 febrile patients were included. Of these, 69 had infective endocarditis, pathologically proven in 28, but with only a clinical diagnosis in 41. In the remaining 74 cases, the diagnosis of-infective endocarditis was rejected after a follow-up of at least 3 months. Results The sensitivity of Duke's criteria was significantly higher, both when patients with possible infective endocarditis were considered as true-positive (definition 1; 100% vs 69%,P |
| doi_str_mv | 10.1093/oxfordjournals.eurheartj.a015411 |
| format | Article |
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Patients A total of 143 consecutive suspected cases of infective endocarditis in 137 febrile patients were included. Of these, 69 had infective endocarditis, pathologically proven in 28, but with only a clinical diagnosis in 41. In the remaining 74 cases, the diagnosis of-infective endocarditis was rejected after a follow-up of at least 3 months. Results The sensitivity of Duke's criteria was significantly higher, both when patients with possible infective endocarditis were considered as true-positive (definition 1; 100% vs 69%,P<0·001) and when possible cases were considered as rejected (definition 2; 76% vs 51%, P<0·01). Specificity was very high with both criteria: 92% Von Reyn vs 88% Duke (ns) with definition 1 and 99% Von Reyn vs 97% Duke (ns) with definition 2. The overall accuracy of the Duke criteria in the entire population was significantly higher with both definitions (0·94 vs 0·81 definition 1, P<0·001; 0·87 vs 0·75, P=0·015 definition 2). Conclusion Duke's criteria for defining infective endocarditis has been shown to be more sensitive than previously adopted criteria, while maintaining a high degree of specificity. Therefore, they must be accepted as a substitute for previous criteria.</description><identifier>ISSN: 0195-668X</identifier><identifier>EISSN: 1522-9645</identifier><identifier>DOI: 10.1093/oxfordjournals.eurheartj.a015411</identifier><language>eng</language><publisher>Oxford University Press</publisher><subject>case definition ; Infective endocarditis ; new Duke criteria specificity</subject><ispartof>European heart journal, 1997-07, Vol.18 (7), p.1149-1156</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids></links><search><creatorcontrib>Cecchi, E.</creatorcontrib><creatorcontrib>Parrini, I.</creatorcontrib><creatorcontrib>Chinaglia, A.</creatorcontrib><creatorcontrib>Pomari, F.</creatorcontrib><creatorcontrib>Brusasco, G.</creatorcontrib><creatorcontrib>Bobbio, M.</creatorcontrib><creatorcontrib>Trinchero, R.</creatorcontrib><creatorcontrib>Brusca, A.</creatorcontrib><title>New diagnostic criteria for infective endocarditis</title><title>European heart journal</title><description>Objective The purpose of this study was to determine the sensitivity and specificity of new criteria proposed by Duke University for case definition of infective endocarditis as compared to the previously accepted Von Reyn criteria. Patients A total of 143 consecutive suspected cases of infective endocarditis in 137 febrile patients were included. Of these, 69 had infective endocarditis, pathologically proven in 28, but with only a clinical diagnosis in 41. In the remaining 74 cases, the diagnosis of-infective endocarditis was rejected after a follow-up of at least 3 months. Results The sensitivity of Duke's criteria was significantly higher, both when patients with possible infective endocarditis were considered as true-positive (definition 1; 100% vs 69%,P<0·001) and when possible cases were considered as rejected (definition 2; 76% vs 51%, P<0·01). Specificity was very high with both criteria: 92% Von Reyn vs 88% Duke (ns) with definition 1 and 99% Von Reyn vs 97% Duke (ns) with definition 2. The overall accuracy of the Duke criteria in the entire population was significantly higher with both definitions (0·94 vs 0·81 definition 1, P<0·001; 0·87 vs 0·75, P=0·015 definition 2). Conclusion Duke's criteria for defining infective endocarditis has been shown to be more sensitive than previously adopted criteria, while maintaining a high degree of specificity. Therefore, they must be accepted as a substitute for previous criteria.</description><subject>case definition</subject><subject>Infective endocarditis</subject><subject>new Duke criteria specificity</subject><issn>0195-668X</issn><issn>1522-9645</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><recordid>eNqVjbtuwjAUQK0KpIbCP3hkSfBNsCFrCS1T1aFDxGJZyU170xJX1-bRvy8DP8B0lqNzhJiDykCVxcJfOs9t7488uJ-Q4ZG_0HHsM6dALwEeRAI6z9PSLPVIJApKnRqzrh_FJIReKbU2YBKRv-FZtuQ-Bx8iNbJhisjk5LUuaeiwiXRCiUPrG8ctRQpTMe6uS5zd-CTSl-3HZpdSiHixv0wHx3_W8bc1q2Kl7a7eWyj08-t7VdmquNf_BzavSZ4</recordid><startdate>199707</startdate><enddate>199707</enddate><creator>Cecchi, E.</creator><creator>Parrini, I.</creator><creator>Chinaglia, A.</creator><creator>Pomari, F.</creator><creator>Brusasco, G.</creator><creator>Bobbio, M.</creator><creator>Trinchero, R.</creator><creator>Brusca, A.</creator><general>Oxford University Press</general><scope>BSCLL</scope></search><sort><creationdate>199707</creationdate><title>New diagnostic criteria for infective endocarditis</title><author>Cecchi, E. ; Parrini, I. ; Chinaglia, A. ; Pomari, F. ; Brusasco, G. ; Bobbio, M. ; Trinchero, R. ; Brusca, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-istex_primary_ark_67375_HXZ_135BGPDD_D3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>case definition</topic><topic>Infective endocarditis</topic><topic>new Duke criteria specificity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cecchi, E.</creatorcontrib><creatorcontrib>Parrini, I.</creatorcontrib><creatorcontrib>Chinaglia, A.</creatorcontrib><creatorcontrib>Pomari, F.</creatorcontrib><creatorcontrib>Brusasco, G.</creatorcontrib><creatorcontrib>Bobbio, M.</creatorcontrib><creatorcontrib>Trinchero, R.</creatorcontrib><creatorcontrib>Brusca, A.</creatorcontrib><collection>Istex</collection><jtitle>European heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cecchi, E.</au><au>Parrini, I.</au><au>Chinaglia, A.</au><au>Pomari, F.</au><au>Brusasco, G.</au><au>Bobbio, M.</au><au>Trinchero, R.</au><au>Brusca, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>New diagnostic criteria for infective endocarditis</atitle><jtitle>European heart journal</jtitle><date>1997-07</date><risdate>1997</risdate><volume>18</volume><issue>7</issue><spage>1149</spage><epage>1156</epage><pages>1149-1156</pages><issn>0195-668X</issn><eissn>1522-9645</eissn><abstract>Objective The purpose of this study was to determine the sensitivity and specificity of new criteria proposed by Duke University for case definition of infective endocarditis as compared to the previously accepted Von Reyn criteria. Patients A total of 143 consecutive suspected cases of infective endocarditis in 137 febrile patients were included. Of these, 69 had infective endocarditis, pathologically proven in 28, but with only a clinical diagnosis in 41. In the remaining 74 cases, the diagnosis of-infective endocarditis was rejected after a follow-up of at least 3 months. Results The sensitivity of Duke's criteria was significantly higher, both when patients with possible infective endocarditis were considered as true-positive (definition 1; 100% vs 69%,P<0·001) and when possible cases were considered as rejected (definition 2; 76% vs 51%, P<0·01). Specificity was very high with both criteria: 92% Von Reyn vs 88% Duke (ns) with definition 1 and 99% Von Reyn vs 97% Duke (ns) with definition 2. The overall accuracy of the Duke criteria in the entire population was significantly higher with both definitions (0·94 vs 0·81 definition 1, P<0·001; 0·87 vs 0·75, P=0·015 definition 2). Conclusion Duke's criteria for defining infective endocarditis has been shown to be more sensitive than previously adopted criteria, while maintaining a high degree of specificity. Therefore, they must be accepted as a substitute for previous criteria.</abstract><pub>Oxford University Press</pub><doi>10.1093/oxfordjournals.eurheartj.a015411</doi></addata></record> |
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| ispartof | European heart journal, 1997-07, Vol.18 (7), p.1149-1156 |
| issn | 0195-668X 1522-9645 |
| language | eng |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Oxford University Press Journals All Titles (1996-Current) |
| subjects | case definition Infective endocarditis new Duke criteria specificity |
| title | New diagnostic criteria for infective endocarditis |
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