Dual-Modal Biosensor for the Determination of Femtomolar miRNA-126 Based on Electrochemical Impedance Spectroscopy and Electrochemiluminescence with Hybridization Chain Reaction Amplification

In this study, a novel dual-modal electrochemical impedance spectroscopy (EIS) and electrochemiluminescence (ECL) biosensor for sensitive detection of femtomolar miRNA-126 was developed based on hybridization chain reaction (HCR). The capture unit was Fe3O4@SiO2@AuNPs-cDNA, being Fe3O4@SiO2@AuNPs na...

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Veröffentlicht in:	Journal of the Electrochemical Society 2020-12, Vol.167 (16), p.167502
Hauptverfasser:	Zheng, Yanjie, Xu, Yichun, Chen, Li, Yin, Xinyang, Lin, Fei, Weng, Shaohuang, Lin, Xinhua
Format:	Artikel
Sprache:	eng
Schlagworte:	Dual-modal biosensor Electrochemical impedance spectroscopy Electrochemiluminescence Hybridization chain reaction MiRNA-126
Online-Zugang:	Volltext
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