3D printed porous polycaprolactone/oyster shell powder (PCL/OSP) scaffolds for bone tissue engineering

3D printed porous polycaprolactone/oyster shell powder (PCL/OSP) scaffolds for bone tissue engineering

In this work, oyster shell powder (OSP) was used as the bio-filler and combined with polycaprolactone (PCL) through melt blending methodology. The PCL and PCL/OSP scaffolds were prepared using additive manufacturing process. All the 3D printed scaffolds hold a highly porosity and interconnected pore...

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Veröffentlicht in:Materials research express 2018-04, Vol.5 (4), p.45403
Hauptverfasser: Luo, Wenfeng, Zhang, Shuangying, Lan, Yuewei, Huang, Chen, Wang, Chao, Lai, Xuexu, Chen, Hanwei, Ao, Ningjian
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3D printing
bone tissue engineering
oyster shell powder
polycaprolactone
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container_issue 4
container_start_page 45403
container_title Materials research express
container_volume 5
creator Luo, Wenfeng
Zhang, Shuangying
Lan, Yuewei
Huang, Chen
Wang, Chao
Lai, Xuexu
Chen, Hanwei
Ao, Ningjian
description In this work, oyster shell powder (OSP) was used as the bio-filler and combined with polycaprolactone (PCL) through melt blending methodology. The PCL and PCL/OSP scaffolds were prepared using additive manufacturing process. All the 3D printed scaffolds hold a highly porosity and interconnected pore structures. OSP particles are dispersed in the polymer matrix, which helped to improve the degree of crystallinity and mineralization ability of the scaffolds. There was no significant cytotoxicity of the prepared scaffolds towards MG-63 cells, and all the scaffolds showed a well ALP activity. Therefore, PCL/OSP scaffolds had a high potential to be employed in the bone tissue engineering.
doi_str_mv 10.1088/2053-1591/aab916
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subjects 3D printing
bone tissue engineering
oyster shell powder
polycaprolactone
title 3D printed porous polycaprolactone/oyster shell powder (PCL/OSP) scaffolds for bone tissue engineering
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