Anatomical robust optimization to account for nasal cavity filling variation during intensity-modulated proton therapy: a comparison with conventional and adaptive planning strategies

The aim of this study is to develop an anatomical robust optimization method for intensity-modulated proton therapy (IMPT) that accounts for interfraction variations in nasal cavity filling, and to compare it with conventional single-field uniform dose (SFUD) optimization and online plan adaptation....

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Veröffentlicht in:	Physics in medicine & biology 2018-01, Vol.63 (2), p.025020-025020
Hauptverfasser:	van de Water, Steven, Albertini, Francesca, Weber, Damien C, Heijmen, Ben J M, Hoogeman, Mischa S, Lomax, Antony J
Format:	Artikel
Sprache:	eng
Schlagworte:	adaptive radiotherapy Humans IMPT Nasal Cavity - pathology Nasal Cavity - radiation effects nasal cavity filling Nose Neoplasms - radiotherapy plan adaptation proton therapy Proton Therapy - methods Proton Therapy - standards Radiotherapy Dosage Radiotherapy Planning, Computer-Assisted - methods Radiotherapy, Intensity-Modulated - methods Radiotherapy, Intensity-Modulated - standards robust optimization sinonasal tumors
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