Modulation of Heart Fibroblast Migration and Collagen Gel Contraction by IGF-I

Dynamic interactions between cells and the extracellular matrix are essential in the regulation of a number of cellular processes including migration, adhesion, proliferation and differentiation. A variety of factors have been identified which modulate these interactions including transforming growt...

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Veröffentlicht in:	Cell Adhesion and Communication 2000, Vol.7 (6), p.513-523
Hauptverfasser:	Kanekar, Shalini, Borg, Thomas K., Terracio, Louis, Carver, Wayne
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Antigens, CD - biosynthesis Antigens, CD - metabolism Cell Adhesion - drug effects Cell Movement - drug effects Chromones - pharmacology Collagen collagen gel Enzyme Inhibitors - pharmacology Extracellular Matrix - enzymology Female Fibroblast Fibroblasts - cytology Fibroblasts - enzymology Flavonoids - pharmacology Gels IGF Insulin-Like Growth Factor I - pharmacology Integrin alphaV Integrin beta1 - biosynthesis Integrin beta1 - metabolism Matrix Metalloproteinases - metabolism migration Morpholines - pharmacology Myocardium - cytology Myocardium - enzymology Pregnancy Protein-Tyrosine Kinases - metabolism Rats Rats, Sprague-Dawley Receptors, Vitronectin - biosynthesis Receptors, Vitronectin - metabolism Signal Transduction - drug effects Signal Transduction - physiology
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