Reperfusion Ventricular Fibrillation and Electric Countershocks During Coronary Artery Bypass Operations-Association with Postoperative CK-MB Release

Reperfusion ventricular fibrillation during coronary artery bypass surgery is common and electric shocks are often needed to terminate it. Both the fibrillation and the reversing electric shocks are potentially detrimental to the myocardium. In 61 aortocoronary bypass patients with uncomplicated cli...

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Veröffentlicht in:Scandinavian cardiovascular journal : SCJ 1994, Vol.28 (2), p.73-78
Hauptverfasser: Hippeläinen, Mikko J., Tuppuraine, Tapani T., Huttunen, Kaija T.
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container_issue 2
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container_title Scandinavian cardiovascular journal : SCJ
container_volume 28
creator Hippeläinen, Mikko J.
Tuppuraine, Tapani T.
Huttunen, Kaija T.
description Reperfusion ventricular fibrillation during coronary artery bypass surgery is common and electric shocks are often needed to terminate it. Both the fibrillation and the reversing electric shocks are potentially detrimental to the myocardium. In 61 aortocoronary bypass patients with uncomplicated clinical course (no difficulties in weaning from bypass, no ECG changes and no inotropic medication), serial creatine kinase-MB values were recorded. Evaluated explanatory variables were patient age, ejection fraction, aortic occlusion time, perfusion time, number of peripheral anastomoses and of anastomoses to marginal branches, myocardial fibrillation time before aortic cross-clamping, after cross-clamping prior to cardiac arrest and after declamping, and number of defibrillations. The results indicated that reperfusion fibrillation times up to 10 minutes are not harmful, provided that left ventricular decompression is carried out. Too early and thus numerous defibrillations raise creatine kinase-MB levels and probably also damage the myocardium, and therefore should be avoided.
doi_str_mv 10.3109/14017439409100166
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Both the fibrillation and the reversing electric shocks are potentially detrimental to the myocardium. In 61 aortocoronary bypass patients with uncomplicated clinical course (no difficulties in weaning from bypass, no ECG changes and no inotropic medication), serial creatine kinase-MB values were recorded. Evaluated explanatory variables were patient age, ejection fraction, aortic occlusion time, perfusion time, number of peripheral anastomoses and of anastomoses to marginal branches, myocardial fibrillation time before aortic cross-clamping, after cross-clamping prior to cardiac arrest and after declamping, and number of defibrillations. The results indicated that reperfusion fibrillation times up to 10 minutes are not harmful, provided that left ventricular decompression is carried out. Too early and thus numerous defibrillations raise creatine kinase-MB levels and probably also damage the myocardium, and therefore should be avoided.</description><identifier>ISSN: 1401-7431</identifier><identifier>ISSN: 0036-5580</identifier><identifier>EISSN: 1651-2006</identifier><identifier>DOI: 10.3109/14017439409100166</identifier><identifier>PMID: 7863289</identifier><identifier>CODEN: SJTCAO</identifier><language>eng</language><publisher>Stockholm: Informa UK Ltd</publisher><subject>Adult ; Age Factors ; Aged ; Anastomosis, Surgical ; Biological and medical sciences ; CK-MB release ; Coronary Artery Bypass ; coronary artery bypass grafting ; Creatine Kinase - blood ; Electric Countershock ; electric countershocks ; Follow-Up Studies ; Heart Arrest, Induced ; Humans ; Isoenzymes ; Linear Models ; Medical sciences ; Middle Aged ; Multivariate Analysis ; Myocardial Reperfusion Injury - enzymology ; Myocardial Reperfusion Injury - therapy ; Myocardium - enzymology ; Stroke Volume ; Surgery (general aspects). 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Both the fibrillation and the reversing electric shocks are potentially detrimental to the myocardium. In 61 aortocoronary bypass patients with uncomplicated clinical course (no difficulties in weaning from bypass, no ECG changes and no inotropic medication), serial creatine kinase-MB values were recorded. Evaluated explanatory variables were patient age, ejection fraction, aortic occlusion time, perfusion time, number of peripheral anastomoses and of anastomoses to marginal branches, myocardial fibrillation time before aortic cross-clamping, after cross-clamping prior to cardiac arrest and after declamping, and number of defibrillations. The results indicated that reperfusion fibrillation times up to 10 minutes are not harmful, provided that left ventricular decompression is carried out. Too early and thus numerous defibrillations raise creatine kinase-MB levels and probably also damage the myocardium, and therefore should be avoided.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Anastomosis, Surgical</subject><subject>Biological and medical sciences</subject><subject>CK-MB release</subject><subject>Coronary Artery Bypass</subject><subject>coronary artery bypass grafting</subject><subject>Creatine Kinase - blood</subject><subject>Electric Countershock</subject><subject>electric countershocks</subject><subject>Follow-Up Studies</subject><subject>Heart Arrest, Induced</subject><subject>Humans</subject><subject>Isoenzymes</subject><subject>Linear Models</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Myocardial Reperfusion Injury - enzymology</subject><subject>Myocardial Reperfusion Injury - therapy</subject><subject>Myocardium - enzymology</subject><subject>Stroke Volume</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the heart</subject><subject>Time Factors</subject><subject>Ventricular Fibrillation - enzymology</subject><subject>Ventricular Fibrillation - therapy</subject><subject>ventricular fibrillation time</subject><subject>Ventricular Function, Left - physiology</subject><issn>1401-7431</issn><issn>0036-5580</issn><issn>1651-2006</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1O3DAUhS3UilLKA3RRyYtuQ33j_Niim2GAtoKKChW2keM4jKnHHl0noHmQvi-eZoqEkFhd637nHPkeQj4CO-TA5BcoGNQFlwWTwBhU1Q7Zg6qELGesepPeiWdJAO_I-xjvkqQUJeyS3VpUPBdyj_y9MiuD_Rht8PTG-AGtHp1CemZbtM6pYQOU7-ipM3pD6TyMfjAYF0H_ifRkROtv0xKDV7imM0xsTY_XKxUjvUzh_yJiNosxaDvlPdhhQX-FOISJ3xs6P89-HtMr44yK5gN52ysXzcF27pPrs9Pf8-_ZxeW3H_PZRaa5lEMGjHc556IVbVsAGA1drmuQJdNC9LytZClqCXldSS60KPJWatlxk4u2LGoDfJ_AlKsxxIimb1Zol-mMBlizabh50XDyfJo8q7Fdmu7Jsa008c9brqJWrkfltY1PMs5B8iJPsq-TzPo-4FI9BHRdM6i1C_jfw1_7xdEz-8IoNyy0QtPchRF9au2VGx4BEkGqmQ</recordid><startdate>1994</startdate><enddate>1994</enddate><creator>Hippeläinen, Mikko J.</creator><creator>Tuppuraine, Tapani T.</creator><creator>Huttunen, Kaija T.</creator><general>Informa UK Ltd</general><general>Taylor &amp; Francis</general><general>Almqvist &amp; Wiksell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>1994</creationdate><title>Reperfusion Ventricular Fibrillation and Electric Countershocks During Coronary Artery Bypass Operations-Association with Postoperative CK-MB Release</title><author>Hippeläinen, Mikko J. ; Tuppuraine, Tapani T. ; Huttunen, Kaija T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c399t-103d2338b8bb411ec1d2c71950c88f3b6958791276938c842b9c9d3e28b547e13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Anastomosis, Surgical</topic><topic>Biological and medical sciences</topic><topic>CK-MB release</topic><topic>Coronary Artery Bypass</topic><topic>coronary artery bypass grafting</topic><topic>Creatine Kinase - blood</topic><topic>Electric Countershock</topic><topic>electric countershocks</topic><topic>Follow-Up Studies</topic><topic>Heart Arrest, Induced</topic><topic>Humans</topic><topic>Isoenzymes</topic><topic>Linear Models</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Myocardial Reperfusion Injury - enzymology</topic><topic>Myocardial Reperfusion Injury - therapy</topic><topic>Myocardium - enzymology</topic><topic>Stroke Volume</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the heart</topic><topic>Time Factors</topic><topic>Ventricular Fibrillation - enzymology</topic><topic>Ventricular Fibrillation - therapy</topic><topic>ventricular fibrillation time</topic><topic>Ventricular Function, Left - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hippeläinen, Mikko J.</creatorcontrib><creatorcontrib>Tuppuraine, Tapani T.</creatorcontrib><creatorcontrib>Huttunen, Kaija T.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Scandinavian cardiovascular journal : SCJ</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hippeläinen, Mikko J.</au><au>Tuppuraine, Tapani T.</au><au>Huttunen, Kaija T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reperfusion Ventricular Fibrillation and Electric Countershocks During Coronary Artery Bypass Operations-Association with Postoperative CK-MB Release</atitle><jtitle>Scandinavian cardiovascular journal : SCJ</jtitle><addtitle>Scand J Thorac Cardiovasc Surg</addtitle><date>1994</date><risdate>1994</risdate><volume>28</volume><issue>2</issue><spage>73</spage><epage>78</epage><pages>73-78</pages><issn>1401-7431</issn><issn>0036-5580</issn><eissn>1651-2006</eissn><coden>SJTCAO</coden><abstract>Reperfusion ventricular fibrillation during coronary artery bypass surgery is common and electric shocks are often needed to terminate it. Both the fibrillation and the reversing electric shocks are potentially detrimental to the myocardium. In 61 aortocoronary bypass patients with uncomplicated clinical course (no difficulties in weaning from bypass, no ECG changes and no inotropic medication), serial creatine kinase-MB values were recorded. Evaluated explanatory variables were patient age, ejection fraction, aortic occlusion time, perfusion time, number of peripheral anastomoses and of anastomoses to marginal branches, myocardial fibrillation time before aortic cross-clamping, after cross-clamping prior to cardiac arrest and after declamping, and number of defibrillations. The results indicated that reperfusion fibrillation times up to 10 minutes are not harmful, provided that left ventricular decompression is carried out. Too early and thus numerous defibrillations raise creatine kinase-MB levels and probably also damage the myocardium, and therefore should be avoided.</abstract><cop>Stockholm</cop><pub>Informa UK Ltd</pub><pmid>7863289</pmid><doi>10.3109/14017439409100166</doi><tpages>6</tpages></addata></record>
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ispartof Scandinavian cardiovascular journal : SCJ, 1994, Vol.28 (2), p.73-78
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0036-5580
1651-2006
language eng
recordid cdi_informahealthcare_journals_10_3109_14017439409100166
source MEDLINE; Taylor & Francis
subjects Adult
Age Factors
Aged
Anastomosis, Surgical
Biological and medical sciences
CK-MB release
Coronary Artery Bypass
coronary artery bypass grafting
Creatine Kinase - blood
Electric Countershock
electric countershocks
Follow-Up Studies
Heart Arrest, Induced
Humans
Isoenzymes
Linear Models
Medical sciences
Middle Aged
Multivariate Analysis
Myocardial Reperfusion Injury - enzymology
Myocardial Reperfusion Injury - therapy
Myocardium - enzymology
Stroke Volume
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
Time Factors
Ventricular Fibrillation - enzymology
Ventricular Fibrillation - therapy
ventricular fibrillation time
Ventricular Function, Left - physiology
title Reperfusion Ventricular Fibrillation and Electric Countershocks During Coronary Artery Bypass Operations-Association with Postoperative CK-MB Release
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