Effects of low flux-low pressure cardiopulmonary bypass on intracellular acid-base and water metabolism

In eight patients undergoing open heart surgery for elective myocardial revascularization, extra-intracellular acid-base and water metabolism parameters were studied before and after cardiopulmonary bypass procedures. All patients presented a different degree of metabolic acidosis related to plasma...

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Veröffentlicht in:Scandinavian cardiovascular journal : SCJ 1986, Vol.20 (2), p.167-170
Hauptverfasser: Canale, Stefano Del, Fiacadori, Enrico, Medici, Dante, Antonucci, Carla, Beghi, Cesare, Vitali, Piero, Belli, Loredana, Vezzani, Antonella, Campodonico, Riccardo, Guariglia, Achille
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container_title Scandinavian cardiovascular journal : SCJ
container_volume 20
creator Canale, Stefano Del
Fiacadori, Enrico
Medici, Dante
Antonucci, Carla
Beghi, Cesare
Vitali, Piero
Belli, Loredana
Vezzani, Antonella
Campodonico, Riccardo
Guariglia, Achille
description In eight patients undergoing open heart surgery for elective myocardial revascularization, extra-intracellular acid-base and water metabolism parameters were studied before and after cardiopulmonary bypass procedures. All patients presented a different degree of metabolic acidosis related to plasma lactate increase. Intracellular acid-base indexes did not change significantly, though all but one patient showed an intracellular buffers consumption. Both total muscle and extracellular water increased, while intracellular water did not change. It was concluded that low flux-low pressure perfusion CPB was related to a substantial preservation of cell integrity.
doi_str_mv 10.3109/14017438609106496
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Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Cardiopulmonary Bypass - adverse effects</subject><subject>CPB</subject><subject>Female</subject><subject>Humans</subject><subject>intracellular bicarbonate</subject><subject>intracellular water</subject><subject>Lactates - blood</subject><subject>Male</subject><subject>Medical sciences</subject><subject>metabolism</subject><subject>Middle Aged</subject><subject>skeletal muscle</subject><subject>Thoracic and cardiovascular surgery. 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ispartof Scandinavian cardiovascular journal : SCJ, 1986, Vol.20 (2), p.167-170
issn 1401-7431
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language eng
recordid cdi_informahealthcare_journals_10_3109_14017438609106496
source Taylor & Francis; MEDLINE
subjects acid-base
Acidosis - etiology
Acidosis, Respiratory - etiology
Aged
Anesthesia
Anesthesia depending on type of surgery
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Cardiopulmonary Bypass - adverse effects
CPB
Female
Humans
intracellular bicarbonate
intracellular water
Lactates - blood
Male
Medical sciences
metabolism
Middle Aged
skeletal muscle
Thoracic and cardiovascular surgery. Cardiopulmonary bypass
Water-Electrolyte Balance
title Effects of low flux-low pressure cardiopulmonary bypass on intracellular acid-base and water metabolism
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