Microdialysis Assessment of 5-Fluorouracil Release from Thermosensitive Magnetoliposomes Induced by an Electromagnetic Field in Tumor-Bearing Mice

Abstract The current study was designed to evaluate the properties of thermosensitive magnetoliposomes (TMs), a new drug carrier proposed by the authors, in an electromagnetic field pertaining to their selective heating and drug release under an in vivo condition. TMs containing 5-fluorouracil (5-FU...

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Veröffentlicht in:	Journal of drug targeting 1998, Vol.5 (5), p.379-390
Hauptverfasser:	Viroonchatapan, Ekapop, Sato, Hitoshi, Ueno, Masaharu, Adachi, Isao, Murata, Jun, Saiki, Ikuo, Tazawa, Kenji, Horikoshi, Isamu
Format:	Artikel
Sprache:	eng
Schlagworte:	5-fluorouracil Animals Antimetabolites, Antineoplastic - metabolism Antineoplastic agents Biological and medical sciences Chemotherapy dextran magnetite Drug Carriers drug release Electromagnetic Fields electromagnetic induction heating Female Fluorouracil - blood Fluorouracil - metabolism General pharmacology Liposomes Medical sciences melanoma Melanoma, Experimental - blood Melanoma, Experimental - metabolism Mice Mice, Inbred C57BL microdialysis Microdialysis - methods Models, Biological Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Thermometers thermosensitive magnetoliposomes Tumor Cells, Cultured
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