Abnormal Patterns of Immunoglobulin Heavy Chain Gene DNA Fingerprinting During Chronic Phase Chronic Myeloid Leukemia

Using IgH DNA fingerprinting we have previously demonstrated clonal immunoglobulin heavy chain (IgH) gene rearrangements during chronic phase (CP) chronic myeloid leukemia (CML) in patients destined to develop lymphoid blast crisis (L-BC). In view of this we decided to follow a cohort of CP CML pati...

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Veröffentlicht in:	Leukemia & lymphoma 1999, Vol.32 (3-4), p.299-307
Hauptverfasser:	Spencer, Andrew, Szydlo, Richard, Grand, Francis H., Goldman, John M., Melo, Junia V.
Format:	Artikel
Sprache:	eng
Schlagworte:	blast crisis chronic myeloid leukaemia chronic phase DNA Fingerprinting Genes, Immunoglobulin Humans IgH DNA fingerprinting immunoglobin heavy chain gene Immunoglobulin Heavy Chains - genetics interferon Leukemia, Myeloid, Chronic-Phase - genetics Leukemia, Myeloid, Chronic-Phase - immunology Leukemia, Myeloid, Chronic-Phase - therapy
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