The Frequency of Homozygous Deletion of a Developmentally Regulated Vh Gene (Humhv3005) is Increased in Patients with Chronic Idiopathic Thrombocytopenic Purpura

Little is known of the genetic factors that may contribute to the development of chronic idiopathic thrombocytopenic purpura (cITP). We have previously shown that a developmentally regulated Vh gene (Humhv 3005) is absent in 10/41 (24940) of patients with systemic lupus erythematosus while it is abs...

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Veröffentlicht in:	Autoimmunity (Chur, Switzerland) Switzerland), 1996, Vol.24 (4), p.257-263
Hauptverfasser:	Mo, Lian, Leu, Sy-Jye C., Berry, Charles, Liu, Fumin, Olee, Tsaiwei, Yang, Yi-Yuan, Beardsley, Diana S., McMillan, Robert, Woods, Virgil L., Chen, Projen P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoimmune Biological and medical sciences Chronic Disease Female Gene Deletion Gene Expression Regulation, Developmental Gene Frequency Genes, Immunoglobulin Hematologic and hematopoietic diseases Humans idiopathic thrombocytopenic purpura Ig V gene deletion Immunoglobulin Variable Region - genetics Male Medical sciences network Platelet diseases and coagulopathies Polymorphism, Restriction Fragment Length Purpura, Thrombocytopenic, Idiopathic - genetics Purpura, Thrombocytopenic, Idiopathic - immunology restriction fragment length polymorphism
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