EXCESSIVE NAKED MEGAKARYOCYTE NUCLEI IN MYELODYSPLASTIC SYNDROME MIMICKING IDIOPATHIC THROMBOCYTOPENIC PURPURA: A Complicated Pre- and Post-transplantation Course

A boy 3 years 7 months old with thrombocytopenia and history of intracranial hemorrhage who underwent bone marrow transplantation is presented. He was refractory to steroids, immunoglobulin G, vincristine, azathioprine, cyclosporine A, interleukin-11, chemotherapy, and splenectomy. Idiopathic thromb...

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Veröffentlicht in:	Pediatric hematology and oncology 2009-09, Vol.26 (6), p.387-397
Hauptverfasser:	Olcay, Lale, Murat Tuncer, A., Okur, Hamza, Erdemli, Esra, Uysal, Zümrüt, Çetin, Mualla, Duru, Feride, Uçkan Çetinkaya, Duygu
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis Bone Marrow Transplantation - adverse effects Case-Control Studies Cell Nucleus - pathology Child Child, Preschool Diagnosis, Differential dysmegakaryopoiesis Female Flow Cytometry Humans Infant Male Megakaryocytes - pathology myelodysplastic syndrome Myelodysplastic Syndromes - diagnosis Myelodysplastic Syndromes - therapy naked megakaryocyte nuclei Platelet Count Purpura, Thrombocytopenic, Idiopathic - diagnosis Purpura, Thrombocytopenic, Idiopathic - therapy refractory thrombocytopenia
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