Mechanism of Transdermal Controlled Nitroglycerin Administration (III) Control of Skin Permeation Rate and Optimization

Abstract A mathematical model was developed to correlate the drug permeation rate through the skin with the drug release rate from a matrix-type drug delivery system. Experiments were carried out using hairless mouse abdominal skin mounted on a recently-developed and hydrodynamically well-calibrated...

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Veröffentlicht in:Drug development and industrial pharmacy 1985, Vol.11 (6-7), p.1213-1253
Hauptverfasser: Keshary, Prakash R., Huang, Yih C., Chien, Yie W.
Format: Artikel
Sprache:eng
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