Osteoarthritis of the Knee Treated with Tolfenamic Acid
48 patients with osteoarthritis of the knee have been treated with tolfenamic acid, a new antirheumatic drug, and acetylsalicylic acid in a doubleblind study including a placebo period. 14 patients preferred tolfenamic acid, 14 acetylsalicyiic acid, while 3 patients preferred placebo. No change in t...
Gespeichert in:
| Veröffentlicht in: | Scandinavian journal of rheumatology 1972, Vol.1 (3), p.97-99 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 99 |
|---|---|
| container_issue | 3 |
| container_start_page | 97 |
| container_title | Scandinavian journal of rheumatology |
| container_volume | 1 |
| creator | Zachariae, Eva Sylvest, Jesper |
| description | 48 patients with osteoarthritis of the knee have been treated with tolfenamic acid, a new antirheumatic drug, and acetylsalicylic acid in a doubleblind study including a placebo period. 14 patients preferred tolfenamic acid, 14 acetylsalicyiic acid, while 3 patients preferred placebo. No change in the range of movement or circumference of the joint, speed of walking, or the quadriceps muscle strength was found. The investigation seems to indicate that tolfenamic acid has an analgesic effect on degenerative joint disease equal to that of acetylsalicyiic acid, but fewer side effects. |
| doi_str_mv | 10.3109/03009747209103005 |
| format | Article |
| fullrecord | <record><control><sourceid>pubmed_infor</sourceid><recordid>TN_cdi_informahealthcare_journals_10_3109_03009747209103005</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4584209</sourcerecordid><originalsourceid>FETCH-LOGICAL-c316t-b9a10c7714407a369d545499c607d13b2e384b24efa403c30094214dd7a199b23</originalsourceid><addsrcrecordid>eNp9kNtKw0AQhhdRaq0-gBdCXiA6e0i3i96U4gkLvanXYbMHsiXJlt0tpW9vQosgolczzD_fz8yP0C2Ge4pBPAAFEJxxAgIPfXGGxrgAknNOyTkaD7O8XyCX6CrGDQAwwcUIjVgxYz00RnwVk_EypDq45GLmbZZqk310xmTrYGQyOtu7VGdr31jTydapbK6cvkYXVjbR3JzqBH2-PK8Xb_ly9fq-mC9zRfE05ZWQGBTnmDHgkk6FLljBhFBT4BrTihg6YxVhxkoGVA3vMIKZ1lxiISpCJwgffVXwMQZjy21wrQyHEkM5ZFD-yqBn7o7Mdle1Rn8Tp6d7_emou8760Mq9D40ukzw0PtggO-XiYP23_eMPvDaySbWSwZQbvwtdH8c_x30BoDV5lw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Osteoarthritis of the Knee Treated with Tolfenamic Acid</title><source>Taylor & Francis:Master (3349 titles)</source><source>MEDLINE</source><source>Taylor & Francis Medical Library - CRKN</source><creator>Zachariae, Eva ; Sylvest, Jesper</creator><creatorcontrib>Zachariae, Eva ; Sylvest, Jesper</creatorcontrib><description>48 patients with osteoarthritis of the knee have been treated with tolfenamic acid, a new antirheumatic drug, and acetylsalicylic acid in a doubleblind study including a placebo period. 14 patients preferred tolfenamic acid, 14 acetylsalicyiic acid, while 3 patients preferred placebo. No change in the range of movement or circumference of the joint, speed of walking, or the quadriceps muscle strength was found. The investigation seems to indicate that tolfenamic acid has an analgesic effect on degenerative joint disease equal to that of acetylsalicyiic acid, but fewer side effects.</description><identifier>ISSN: 0300-9742</identifier><identifier>EISSN: 1502-7732</identifier><identifier>DOI: 10.3109/03009747209103005</identifier><identifier>PMID: 4584209</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Adult ; Aged ; Alanine Transaminase - blood ; Aspirin - adverse effects ; Aspirin - therapeutic use ; Body Weight ; Clinical Trials as Topic ; Creatinine - blood ; Female ; Glycosuria ; Humans ; Knee Joint ; Leukocyte Count ; Male ; Middle Aged ; ortho-Aminobenzoates - adverse effects ; ortho-Aminobenzoates - therapeutic use ; Osteoarthritis - drug therapy ; Placebos ; Proteinuria</subject><ispartof>Scandinavian journal of rheumatology, 1972, Vol.1 (3), p.97-99</ispartof><rights>1972 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1972</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c316t-b9a10c7714407a369d545499c607d13b2e384b24efa403c30094214dd7a199b23</citedby><cites>FETCH-LOGICAL-c316t-b9a10c7714407a369d545499c607d13b2e384b24efa403c30094214dd7a199b23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/03009747209103005$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/03009747209103005$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,776,780,4010,27900,27901,27902,59620,59726,60409,60515,61194,61229,61375,61410</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4584209$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zachariae, Eva</creatorcontrib><creatorcontrib>Sylvest, Jesper</creatorcontrib><title>Osteoarthritis of the Knee Treated with Tolfenamic Acid</title><title>Scandinavian journal of rheumatology</title><addtitle>Scand J Rheumatol</addtitle><description>48 patients with osteoarthritis of the knee have been treated with tolfenamic acid, a new antirheumatic drug, and acetylsalicylic acid in a doubleblind study including a placebo period. 14 patients preferred tolfenamic acid, 14 acetylsalicyiic acid, while 3 patients preferred placebo. No change in the range of movement or circumference of the joint, speed of walking, or the quadriceps muscle strength was found. The investigation seems to indicate that tolfenamic acid has an analgesic effect on degenerative joint disease equal to that of acetylsalicyiic acid, but fewer side effects.</description><subject>Adult</subject><subject>Aged</subject><subject>Alanine Transaminase - blood</subject><subject>Aspirin - adverse effects</subject><subject>Aspirin - therapeutic use</subject><subject>Body Weight</subject><subject>Clinical Trials as Topic</subject><subject>Creatinine - blood</subject><subject>Female</subject><subject>Glycosuria</subject><subject>Humans</subject><subject>Knee Joint</subject><subject>Leukocyte Count</subject><subject>Male</subject><subject>Middle Aged</subject><subject>ortho-Aminobenzoates - adverse effects</subject><subject>ortho-Aminobenzoates - therapeutic use</subject><subject>Osteoarthritis - drug therapy</subject><subject>Placebos</subject><subject>Proteinuria</subject><issn>0300-9742</issn><issn>1502-7732</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kNtKw0AQhhdRaq0-gBdCXiA6e0i3i96U4gkLvanXYbMHsiXJlt0tpW9vQosgolczzD_fz8yP0C2Ge4pBPAAFEJxxAgIPfXGGxrgAknNOyTkaD7O8XyCX6CrGDQAwwcUIjVgxYz00RnwVk_EypDq45GLmbZZqk310xmTrYGQyOtu7VGdr31jTydapbK6cvkYXVjbR3JzqBH2-PK8Xb_ly9fq-mC9zRfE05ZWQGBTnmDHgkk6FLljBhFBT4BrTihg6YxVhxkoGVA3vMIKZ1lxiISpCJwgffVXwMQZjy21wrQyHEkM5ZFD-yqBn7o7Mdle1Rn8Tp6d7_emou8760Mq9D40ukzw0PtggO-XiYP23_eMPvDaySbWSwZQbvwtdH8c_x30BoDV5lw</recordid><startdate>1972</startdate><enddate>1972</enddate><creator>Zachariae, Eva</creator><creator>Sylvest, Jesper</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>1972</creationdate><title>Osteoarthritis of the Knee Treated with Tolfenamic Acid</title><author>Zachariae, Eva ; Sylvest, Jesper</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c316t-b9a10c7714407a369d545499c607d13b2e384b24efa403c30094214dd7a199b23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Alanine Transaminase - blood</topic><topic>Aspirin - adverse effects</topic><topic>Aspirin - therapeutic use</topic><topic>Body Weight</topic><topic>Clinical Trials as Topic</topic><topic>Creatinine - blood</topic><topic>Female</topic><topic>Glycosuria</topic><topic>Humans</topic><topic>Knee Joint</topic><topic>Leukocyte Count</topic><topic>Male</topic><topic>Middle Aged</topic><topic>ortho-Aminobenzoates - adverse effects</topic><topic>ortho-Aminobenzoates - therapeutic use</topic><topic>Osteoarthritis - drug therapy</topic><topic>Placebos</topic><topic>Proteinuria</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zachariae, Eva</creatorcontrib><creatorcontrib>Sylvest, Jesper</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Scandinavian journal of rheumatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zachariae, Eva</au><au>Sylvest, Jesper</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Osteoarthritis of the Knee Treated with Tolfenamic Acid</atitle><jtitle>Scandinavian journal of rheumatology</jtitle><addtitle>Scand J Rheumatol</addtitle><date>1972</date><risdate>1972</risdate><volume>1</volume><issue>3</issue><spage>97</spage><epage>99</epage><pages>97-99</pages><issn>0300-9742</issn><eissn>1502-7732</eissn><abstract>48 patients with osteoarthritis of the knee have been treated with tolfenamic acid, a new antirheumatic drug, and acetylsalicylic acid in a doubleblind study including a placebo period. 14 patients preferred tolfenamic acid, 14 acetylsalicyiic acid, while 3 patients preferred placebo. No change in the range of movement or circumference of the joint, speed of walking, or the quadriceps muscle strength was found. The investigation seems to indicate that tolfenamic acid has an analgesic effect on degenerative joint disease equal to that of acetylsalicyiic acid, but fewer side effects.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>4584209</pmid><doi>10.3109/03009747209103005</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0300-9742 |
| ispartof | Scandinavian journal of rheumatology, 1972, Vol.1 (3), p.97-99 |
| issn | 0300-9742 1502-7732 |
| language | eng |
| recordid | cdi_informahealthcare_journals_10_3109_03009747209103005 |
| source | Taylor & Francis:Master (3349 titles); MEDLINE; Taylor & Francis Medical Library - CRKN |
| subjects | Adult Aged Alanine Transaminase - blood Aspirin - adverse effects Aspirin - therapeutic use Body Weight Clinical Trials as Topic Creatinine - blood Female Glycosuria Humans Knee Joint Leukocyte Count Male Middle Aged ortho-Aminobenzoates - adverse effects ortho-Aminobenzoates - therapeutic use Osteoarthritis - drug therapy Placebos Proteinuria |
| title | Osteoarthritis of the Knee Treated with Tolfenamic Acid |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T08%3A50%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_infor&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Osteoarthritis%20of%20the%20Knee%20Treated%20with%20Tolfenamic%20Acid&rft.jtitle=Scandinavian%20journal%20of%20rheumatology&rft.au=Zachariae,%20Eva&rft.date=1972&rft.volume=1&rft.issue=3&rft.spage=97&rft.epage=99&rft.pages=97-99&rft.issn=0300-9742&rft.eissn=1502-7732&rft_id=info:doi/10.3109/03009747209103005&rft_dat=%3Cpubmed_infor%3E4584209%3C/pubmed_infor%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/4584209&rfr_iscdi=true |