A Comparison of Two Delivery Methods for Aerosolized Metaproterenol Sulfate
The bronchodilator response to metaproterenol sulfate delivered by metered-dose inhaler (MDI) with a spacer device (Aerochamber®) and by jet nebulizer was studied in 15 asthmatic patients. The mean percent increase in absolute forced expiratory volume in 1 second (FEV1) with an MDI plus Aerochamber...
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| Veröffentlicht in: | The Journal of asthma 1986, Vol.23 (6), p.297-301 |
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| container_title | The Journal of asthma |
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| creator | Salzman, Gaiy A. Pyszczynski, Dennis R. |
| description | The bronchodilator response to metaproterenol sulfate delivered by metered-dose inhaler (MDI) with a spacer device (Aerochamber®) and by jet nebulizer was studied in 15 asthmatic patients. The mean percent increase in absolute forced expiratory volume in 1 second (FEV1) with an MDI plus Aerochamber was 28.6%, and 28.8% with jet nebuliza-tion. There were no significant differences in the mean percent increases in FEV1, forced vital capacity (FVC), maximum midflow rate (MMFR), and peak expiratory flow rate (PEFR) with the two delivery methods. It is concluded that there is no difference in the bronchodilator responses to metaproterenol sulfate delivered by MDI plus Aerochamber or by jet nebulizer. The MDI plus Aerochamber has the advantage of being less expensive and more convenient to use. |
| doi_str_mv | 10.3109/02770908609073176 |
| format | Article |
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The mean percent increase in absolute forced expiratory volume in 1 second (FEV1) with an MDI plus Aerochamber was 28.6%, and 28.8% with jet nebuliza-tion. There were no significant differences in the mean percent increases in FEV1, forced vital capacity (FVC), maximum midflow rate (MMFR), and peak expiratory flow rate (PEFR) with the two delivery methods. It is concluded that there is no difference in the bronchodilator responses to metaproterenol sulfate delivered by MDI plus Aerochamber or by jet nebulizer. 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Drug treatments ; Respiration - drug effects ; Respiratory system</subject><ispartof>The Journal of asthma, 1986, Vol.23 (6), p.297-301</ispartof><rights>1986 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1986</rights><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-142609420920dc517119ff56d98071c2227e4def28cb15209240873c747305383</citedby><cites>FETCH-LOGICAL-c440t-142609420920dc517119ff56d98071c2227e4def28cb15209240873c747305383</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/02770908609073176$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/02770908609073176$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,776,780,4010,27900,27901,27902,59620,59726,60409,60515,61194,61229,61375,61410</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8050325$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3818510$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Salzman, Gaiy A.</creatorcontrib><creatorcontrib>Pyszczynski, Dennis R.</creatorcontrib><title>A Comparison of Two Delivery Methods for Aerosolized Metaproterenol Sulfate</title><title>The Journal of asthma</title><addtitle>J Asthma</addtitle><description>The bronchodilator response to metaproterenol sulfate delivered by metered-dose inhaler (MDI) with a spacer device (Aerochamber®) and by jet nebulizer was studied in 15 asthmatic patients. The mean percent increase in absolute forced expiratory volume in 1 second (FEV1) with an MDI plus Aerochamber was 28.6%, and 28.8% with jet nebuliza-tion. There were no significant differences in the mean percent increases in FEV1, forced vital capacity (FVC), maximum midflow rate (MMFR), and peak expiratory flow rate (PEFR) with the two delivery methods. It is concluded that there is no difference in the bronchodilator responses to metaproterenol sulfate delivered by MDI plus Aerochamber or by jet nebulizer. The MDI plus Aerochamber has the advantage of being less expensive and more convenient to use.</description><subject>Aerosols</subject><subject>Asthma - drug therapy</subject><subject>Biological and medical sciences</subject><subject>Bronchodilator Agents - administration & dosage</subject><subject>Bronchodilator Agents - therapeutic use</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Metaproterenol - administration & dosage</subject><subject>Metaproterenol - therapeutic use</subject><subject>Nebulizers and Vaporizers</subject><subject>Pharmacology. Drug treatments</subject><subject>Respiration - drug effects</subject><subject>Respiratory system</subject><issn>0277-0903</issn><issn>1532-4303</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtrGzEUhUVpcJ2kP6CLwixKdpNcPcbS0G6M82iIQxZ114OsucJjNCNXmklwfn1k7BpKIRsJ7vnO5dxDyBcKl5xCeQVMSihBTdIjOZWTD2RMC85ywYF_JOOdnieNfyKnMa4B0gAmIzLiiqqCwpg8TLOZbzc6NNF3mbfZ4sVn1-iaZwzb7BH7la9jZn3Iphh89K55xXo315vgewzYeZf9GpzVPZ6TE6tdxM-H_4z8vr1ZzH7m86e7-9l0nhshoM-pYCmvYFAyqE1BJaWltcWkLhVIahhjEkWNlimzpMUOE6AkN1JIDgVX_Ixc7PemCH8GjH3VNtGgc7pDP8RKSqZYKUQC6R40KXoMaKtNaFodthWFaldg9V-ByfP1sHxYtlgfHYfGkv7toOtotLNBd6aJR0xBAZwVCfuxx5ouldfqFx9cXfV663z46-Hvpfj-j32F2vUrowNWaz-ELtX7zg1v9YOakw</recordid><startdate>1986</startdate><enddate>1986</enddate><creator>Salzman, Gaiy A.</creator><creator>Pyszczynski, Dennis R.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><general>Informa Healthcare</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1986</creationdate><title>A Comparison of Two Delivery Methods for Aerosolized Metaproterenol Sulfate</title><author>Salzman, Gaiy A. ; Pyszczynski, Dennis R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-142609420920dc517119ff56d98071c2227e4def28cb15209240873c747305383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Aerosols</topic><topic>Asthma - drug therapy</topic><topic>Biological and medical sciences</topic><topic>Bronchodilator Agents - administration & dosage</topic><topic>Bronchodilator Agents - therapeutic use</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Metaproterenol - administration & dosage</topic><topic>Metaproterenol - therapeutic use</topic><topic>Nebulizers and Vaporizers</topic><topic>Pharmacology. Drug treatments</topic><topic>Respiration - drug effects</topic><topic>Respiratory system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Salzman, Gaiy A.</creatorcontrib><creatorcontrib>Pyszczynski, Dennis R.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of asthma</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Salzman, Gaiy A.</au><au>Pyszczynski, Dennis R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Comparison of Two Delivery Methods for Aerosolized Metaproterenol Sulfate</atitle><jtitle>The Journal of asthma</jtitle><addtitle>J Asthma</addtitle><date>1986</date><risdate>1986</risdate><volume>23</volume><issue>6</issue><spage>297</spage><epage>301</epage><pages>297-301</pages><issn>0277-0903</issn><eissn>1532-4303</eissn><coden>JOUADU</coden><abstract>The bronchodilator response to metaproterenol sulfate delivered by metered-dose inhaler (MDI) with a spacer device (Aerochamber®) and by jet nebulizer was studied in 15 asthmatic patients. The mean percent increase in absolute forced expiratory volume in 1 second (FEV1) with an MDI plus Aerochamber was 28.6%, and 28.8% with jet nebuliza-tion. There were no significant differences in the mean percent increases in FEV1, forced vital capacity (FVC), maximum midflow rate (MMFR), and peak expiratory flow rate (PEFR) with the two delivery methods. It is concluded that there is no difference in the bronchodilator responses to metaproterenol sulfate delivered by MDI plus Aerochamber or by jet nebulizer. The MDI plus Aerochamber has the advantage of being less expensive and more convenient to use.</abstract><cop>New York, NY</cop><pub>Informa UK Ltd</pub><pmid>3818510</pmid><doi>10.3109/02770908609073176</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0277-0903 |
| ispartof | The Journal of asthma, 1986, Vol.23 (6), p.297-301 |
| issn | 0277-0903 1532-4303 |
| language | eng |
| recordid | cdi_informahealthcare_journals_10_3109_02770908609073176 |
| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
| subjects | Aerosols Asthma - drug therapy Biological and medical sciences Bronchodilator Agents - administration & dosage Bronchodilator Agents - therapeutic use Humans Medical sciences Metaproterenol - administration & dosage Metaproterenol - therapeutic use Nebulizers and Vaporizers Pharmacology. Drug treatments Respiration - drug effects Respiratory system |
| title | A Comparison of Two Delivery Methods for Aerosolized Metaproterenol Sulfate |
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