The Metabolism of Tolamolol in the Mouse, Rat, Guinea-pig, Rabbit and Dog

1. [3H, 14C]Tolamolol was well absorbed after oral administration to mice, rats, guinea-pigs, rabbits and dogs. 2. The major route for excretion of. radioactivity by mice, rats and guineapigs was the faeces; in rabbits the major route was the urine. Dogs excreted similar amounts of radioactivity by...

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Veröffentlicht in:	Xenobiotica 1975-01, Vol.5 (3), p.183-195
Hauptverfasser:	Wood, B. A., Stopher, D. A., Monro, A. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bile - metabolism Chemical Phenomena Chemistry Dogs Feces - metabolism Glucuronates Guinea Pigs Hydroxylation Intestinal Absorption Mice Propanolamines - blood Propanolamines - metabolism Propanolamines - urine Rabbits Rats Species Specificity Sulfates
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