Cinnarizine in the prophylaxis of car sickness in children
Summary An open study was carried out in 79 children known to be susceptible to car sickness to assess the efficacy and tolerance of cinnarizine used prophylactically. Each child received one 15 mg cinnarizine tablet 2 hours before a long car journey and a further half-tablet every 8 hours thereafte...
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| Veröffentlicht in: | Current medical research and opinion 1983, Vol.8 (7), p.451-455 |
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| container_title | Current medical research and opinion |
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| creator | Macnair, Alexander L. |
| description | Summary
An open study was carried out in 79 children known to be susceptible to car sickness to assess the efficacy and tolerance of cinnarizine used prophylactically. Each child received one 15 mg cinnarizine tablet 2 hours before a long car journey and a further half-tablet every 8 hours thereafter; if required. The results of the children's assessments indicated that 81% considered the preparation either ‘good' or ‘excellent ‘and 69% of the 68 who had previously received other medication for travel sickness rated it ‘better’ or ‘much better’. Only 4% of the children vomited and only 14% felt sleepy or drowsy. All but 3 of the 52 doctors who participated were prepared to give cinnarizine again to their charges based on the experience of this study. |
| doi_str_mv | 10.1185/03007998309109781 |
| format | Article |
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An open study was carried out in 79 children known to be susceptible to car sickness to assess the efficacy and tolerance of cinnarizine used prophylactically. Each child received one 15 mg cinnarizine tablet 2 hours before a long car journey and a further half-tablet every 8 hours thereafter; if required. The results of the children's assessments indicated that 81% considered the preparation either ‘good' or ‘excellent ‘and 69% of the 68 who had previously received other medication for travel sickness rated it ‘better’ or ‘much better’. Only 4% of the children vomited and only 14% felt sleepy or drowsy. All but 3 of the 52 doctors who participated were prepared to give cinnarizine again to their charges based on the experience of this study.</description><identifier>ISSN: 0300-7995</identifier><identifier>EISSN: 1473-4877</identifier><identifier>DOI: 10.1185/03007998309109781</identifier><identifier>PMID: 6627971</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Child ; Child, Preschool ; Cinnarizine ; Cinnarizine - therapeutic use ; Female ; Humans ; Male ; motion sickness ; Motion Sickness - drug therapy ; Motion Sickness - prevention & control ; Piperazines - therapeutic use</subject><ispartof>Current medical research and opinion, 1983, Vol.8 (7), p.451-455</ispartof><rights>1983 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1983</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c401t-a802aed5fa077cb04a812850895c58caad00eb24744a0bbaf3ce60a9b8aafdab3</citedby><cites>FETCH-LOGICAL-c401t-a802aed5fa077cb04a812850895c58caad00eb24744a0bbaf3ce60a9b8aafdab3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1185/03007998309109781$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1185/03007998309109781$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,776,780,4010,27900,27901,27902,59620,59726,60409,60515,61194,61229,61375,61410</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6627971$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Macnair, Alexander L.</creatorcontrib><title>Cinnarizine in the prophylaxis of car sickness in children</title><title>Current medical research and opinion</title><addtitle>Curr Med Res Opin</addtitle><description>Summary
An open study was carried out in 79 children known to be susceptible to car sickness to assess the efficacy and tolerance of cinnarizine used prophylactically. Each child received one 15 mg cinnarizine tablet 2 hours before a long car journey and a further half-tablet every 8 hours thereafter; if required. The results of the children's assessments indicated that 81% considered the preparation either ‘good' or ‘excellent ‘and 69% of the 68 who had previously received other medication for travel sickness rated it ‘better’ or ‘much better’. Only 4% of the children vomited and only 14% felt sleepy or drowsy. All but 3 of the 52 doctors who participated were prepared to give cinnarizine again to their charges based on the experience of this study.</description><subject>Child</subject><subject>Child, Preschool</subject><subject>Cinnarizine</subject><subject>Cinnarizine - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>motion sickness</subject><subject>Motion Sickness - drug therapy</subject><subject>Motion Sickness - prevention & control</subject><subject>Piperazines - therapeutic use</subject><issn>0300-7995</issn><issn>1473-4877</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLxDAUhYMo4zj6A1wIXbmr3vSVRN3I4AsG3Og63KYpjbbpmLTo-OvNMIMgwqzO4jw4fIScUriglOeXkAIwIXgKgoJgnO6RKc1YGmecsX0yXftxCOSH5Mj7NwCacCEmZFIUCROMTsnV3FiLznwbqyNjo6HR0dL1y2bV4pfxUV9HCl3kjXq32vt1RDWmrZy2x-Sgxtbrk63OyOv93cv8MV48PzzNbxexyoAOMXJIUFd5jcCYKiFDHl7kwEWucq4QKwBdJhnLMoSyxDpVugAUJUesKyzTGTnf7IZfH6P2g-yMV7pt0ep-9JIDg4IleQjSTVC53nuna7l0pkO3khTkmpf8xyt0zrbjY9np6rexBRT8m41vbN27Dj9711ZywFXbu9qhVcbLdNf89Z96o7EdmkBUy7d-dDZw23HuB8Uwi1c</recordid><startdate>1983</startdate><enddate>1983</enddate><creator>Macnair, Alexander L.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1983</creationdate><title>Cinnarizine in the prophylaxis of car sickness in children</title><author>Macnair, Alexander L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c401t-a802aed5fa077cb04a812850895c58caad00eb24744a0bbaf3ce60a9b8aafdab3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Child</topic><topic>Child, Preschool</topic><topic>Cinnarizine</topic><topic>Cinnarizine - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>motion sickness</topic><topic>Motion Sickness - drug therapy</topic><topic>Motion Sickness - prevention & control</topic><topic>Piperazines - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Macnair, Alexander L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Current medical research and opinion</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Macnair, Alexander L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cinnarizine in the prophylaxis of car sickness in children</atitle><jtitle>Current medical research and opinion</jtitle><addtitle>Curr Med Res Opin</addtitle><date>1983</date><risdate>1983</risdate><volume>8</volume><issue>7</issue><spage>451</spage><epage>455</epage><pages>451-455</pages><issn>0300-7995</issn><eissn>1473-4877</eissn><abstract>Summary
An open study was carried out in 79 children known to be susceptible to car sickness to assess the efficacy and tolerance of cinnarizine used prophylactically. Each child received one 15 mg cinnarizine tablet 2 hours before a long car journey and a further half-tablet every 8 hours thereafter; if required. The results of the children's assessments indicated that 81% considered the preparation either ‘good' or ‘excellent ‘and 69% of the 68 who had previously received other medication for travel sickness rated it ‘better’ or ‘much better’. Only 4% of the children vomited and only 14% felt sleepy or drowsy. All but 3 of the 52 doctors who participated were prepared to give cinnarizine again to their charges based on the experience of this study.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>6627971</pmid><doi>10.1185/03007998309109781</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0300-7995 |
| ispartof | Current medical research and opinion, 1983, Vol.8 (7), p.451-455 |
| issn | 0300-7995 1473-4877 |
| language | eng |
| recordid | cdi_informahealthcare_journals_10_1185_03007998309109781 |
| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
| subjects | Child Child, Preschool Cinnarizine Cinnarizine - therapeutic use Female Humans Male motion sickness Motion Sickness - drug therapy Motion Sickness - prevention & control Piperazines - therapeutic use |
| title | Cinnarizine in the prophylaxis of car sickness in children |
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