mRNA expression profile of a human cancer cell line in response to Ginkgo biloba extract: Induction of antioxidant response and the golgi system

Supplementation of diets with plant extracts for health and prevention of degenerative diseases is popular. However the molecular basis of their therapeutic potentials are poorly defined. We hypothesized that in vitro assays that enable quantitative analysis of the gene expression profiles combined...

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Veröffentlicht in:	Free radical research 2000-01, Vol.33 (6), p.831-849
Hauptverfasser:	Gohil, Kishorchandra, Moy, Ronald K., Farzin, Sahar, Maguire, John J., Packer, Lester
Format:	Artikel
Sprache:	eng
Schlagworte:	activated ras Antioxidants - metabolism Cell Division dietary antioxidants DNA - biosynthesis DNA Damage - drug effects DNA Repair - drug effects Flavonoids - pharmacology Flow Cytometry Ginkgo biloba - chemistry Glutamate-Cysteine Ligase - genetics Glutathione - metabolism Golgi Apparatus - drug effects Golgi Apparatus - physiology Heme Oxygenase (Decyclizing) - genetics Heme Oxygenase-1 Humans Membrane Proteins oligonucleotide arrays Plant Extracts - pharmacology Plants, Medicinal reactive oxygen species RNA, Messenger - analysis Superoxide Dismutase - genetics Tumor Cells, Cultured Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - pathology
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