Adaptive Response in Mouse Embryos?
Pre-implantation embryos of the mouse were studied for the occurrence of an adaptive response, i.e. induction of radio-resistance by a previous low dose. Various experimental designs were checked (initial doses between 3 and 10 cGy; second dose 2-6 Gy at 6-24 h after the first dose). Some of the exp...
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| Veröffentlicht in: | International journal of radiation biology 1992, Vol.62 (2), p.169-175 |
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| container_end_page | 175 |
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| container_title | International journal of radiation biology |
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| creator | Müller, W.-U. Streffer, C. Niedereichholz, F. |
| description | Pre-implantation embryos of the mouse were studied for the occurrence of an adaptive response, i.e. induction of radio-resistance by a previous low dose. Various experimental designs were checked (initial doses between 3 and 10 cGy; second dose 2-6 Gy at 6-24 h after the first dose). Some of the experiments were carried out in exactly the same way that resulted in an adaptive response of human lymphocytes reported previously. However, when cell proliferation and differentiation of mouse embryos were examined, none of the conditions tested indicated the induction of an adaptive response. |
| doi_str_mv | 10.1080/09553009214551981 |
| format | Article |
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Various experimental designs were checked (initial doses between 3 and 10 cGy; second dose 2-6 Gy at 6-24 h after the first dose). Some of the experiments were carried out in exactly the same way that resulted in an adaptive response of human lymphocytes reported previously. However, when cell proliferation and differentiation of mouse embryos were examined, none of the conditions tested indicated the induction of an adaptive response.</description><identifier>ISSN: 0955-3002</identifier><identifier>EISSN: 1362-3095</identifier><identifier>DOI: 10.1080/09553009214551981</identifier><identifier>PMID: 1355510</identifier><language>eng</language><publisher>LONDON: Informa UK Ltd</publisher><subject>Adaptation, Physiological - physiology ; Animals ; Biological and medical sciences ; Biological effects of radiation ; Biology ; Blastocyst - physiology ; Blastocyst - radiation effects ; Fundamental and applied biological sciences. Psychology ; Ionizing radiations ; Life Sciences & Biomedicine ; Life Sciences & Biomedicine - Other Topics ; Mice ; Mice, Inbred Strains ; Nuclear Science & Technology ; Radiation Tolerance - physiology ; Radiology, Nuclear Medicine & Medical Imaging ; Science & Technology ; Space life sciences ; Technology ; Tissues, organs and organisms biophysics</subject><ispartof>International journal of radiation biology, 1992, Vol.62 (2), p.169-175</ispartof><rights>1992 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1992</rights><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>14</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wosA1992JL58100006</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c461t-94b1b51ac2801c56eee763736c055534e3020b1476db54677373faf32974dd83</citedby><cites>FETCH-LOGICAL-c461t-94b1b51ac2801c56eee763736c055534e3020b1476db54677373faf32974dd83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/09553009214551981$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/09553009214551981$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,780,784,4024,27923,27924,27925,59647,59753,60436,60542,61221,61256,61402,61437</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4337237$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1355510$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Müller, W.-U.</creatorcontrib><creatorcontrib>Streffer, C.</creatorcontrib><creatorcontrib>Niedereichholz, F.</creatorcontrib><title>Adaptive Response in Mouse Embryos?</title><title>International journal of radiation biology</title><addtitle>INT J RADIAT BIOL</addtitle><addtitle>Int J Radiat Biol</addtitle><description>Pre-implantation embryos of the mouse were studied for the occurrence of an adaptive response, i.e. induction of radio-resistance by a previous low dose. Various experimental designs were checked (initial doses between 3 and 10 cGy; second dose 2-6 Gy at 6-24 h after the first dose). Some of the experiments were carried out in exactly the same way that resulted in an adaptive response of human lymphocytes reported previously. However, when cell proliferation and differentiation of mouse embryos were examined, none of the conditions tested indicated the induction of an adaptive response.</description><subject>Adaptation, Physiological - physiology</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Biological effects of radiation</subject><subject>Biology</subject><subject>Blastocyst - physiology</subject><subject>Blastocyst - radiation effects</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Ionizing radiations</subject><subject>Life Sciences & Biomedicine</subject><subject>Life Sciences & Biomedicine - Other Topics</subject><subject>Mice</subject><subject>Mice, Inbred Strains</subject><subject>Nuclear Science & Technology</subject><subject>Radiation Tolerance - physiology</subject><subject>Radiology, Nuclear Medicine & Medical Imaging</subject><subject>Science & Technology</subject><subject>Space life sciences</subject><subject>Technology</subject><subject>Tissues, organs and organisms biophysics</subject><issn>0955-3002</issn><issn>1362-3095</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EZCTM</sourceid><sourceid>EIF</sourceid><recordid>eNqNkV1L5DAUhoO46OzoD_BCGHDZGxnNaT7aorAMg-6uzCKI9yVNTzHSJmPSrsy_34ydVURQr3Lgfd7z8YaQA6AnQDN6SnMhGKV5AlwIyDPYIiNgMpmyqGyT0VqPNU12ydcQ7mmsKMt2yA4wEQ10RI5mlVp25i9ObjAsnQ04MXbyx_WxuGhLv3Lhxx75Uqsm4P7mHZPby4vb-a_p4vrn7_lsMdVcQjfNeQmlAKWTjIIWEhFTyVImNY3DGEcWp5fAU1mVgss0jVqtapbkKa-qjI3J96Ht0ruHHkNXtCZobBplMe5TpAwkExl8CIJMcr7uPiYwgNq7EDzWxdKbVvlVAbRYB1i8CTB6DjfN-7LF6sUxJBb1bxtdBa2a2iurTXjGOGNp8jT6eMAesXR10AatxmdqBnmeXC3iMfFLqIx09nl6bjrVGWfnrrddtJ4PVmNr51v16HxTFZ1aNc7_X469d-7ZK_sdqqa708pjce96b-N_vxPWP-Z4um4</recordid><startdate>1992</startdate><enddate>1992</enddate><creator>Müller, W.-U.</creator><creator>Streffer, C.</creator><creator>Niedereichholz, F.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>BLEPL</scope><scope>DTL</scope><scope>EZCTM</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>1992</creationdate><title>Adaptive Response in Mouse Embryos?</title><author>Müller, W.-U. ; Streffer, C. ; Niedereichholz, F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c461t-94b1b51ac2801c56eee763736c055534e3020b1476db54677373faf32974dd83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adaptation, Physiological - physiology</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Biological effects of radiation</topic><topic>Biology</topic><topic>Blastocyst - physiology</topic><topic>Blastocyst - radiation effects</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Ionizing radiations</topic><topic>Life Sciences & Biomedicine</topic><topic>Life Sciences & Biomedicine - Other Topics</topic><topic>Mice</topic><topic>Mice, Inbred Strains</topic><topic>Nuclear Science & Technology</topic><topic>Radiation Tolerance - physiology</topic><topic>Radiology, Nuclear Medicine & Medical Imaging</topic><topic>Science & Technology</topic><topic>Space life sciences</topic><topic>Technology</topic><topic>Tissues, organs and organisms biophysics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Müller, W.-U.</creatorcontrib><creatorcontrib>Streffer, C.</creatorcontrib><creatorcontrib>Niedereichholz, F.</creatorcontrib><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Web of Science - Science Citation Index Expanded - 1992</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of radiation biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Müller, W.-U.</au><au>Streffer, C.</au><au>Niedereichholz, F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adaptive Response in Mouse Embryos?</atitle><jtitle>International journal of radiation biology</jtitle><stitle>INT J RADIAT BIOL</stitle><addtitle>Int J Radiat Biol</addtitle><date>1992</date><risdate>1992</risdate><volume>62</volume><issue>2</issue><spage>169</spage><epage>175</epage><pages>169-175</pages><issn>0955-3002</issn><eissn>1362-3095</eissn><abstract>Pre-implantation embryos of the mouse were studied for the occurrence of an adaptive response, i.e. induction of radio-resistance by a previous low dose. Various experimental designs were checked (initial doses between 3 and 10 cGy; second dose 2-6 Gy at 6-24 h after the first dose). Some of the experiments were carried out in exactly the same way that resulted in an adaptive response of human lymphocytes reported previously. However, when cell proliferation and differentiation of mouse embryos were examined, none of the conditions tested indicated the induction of an adaptive response.</abstract><cop>LONDON</cop><pub>Informa UK Ltd</pub><pmid>1355510</pmid><doi>10.1080/09553009214551981</doi><tpages>7</tpages></addata></record> |
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| ispartof | International journal of radiation biology, 1992, Vol.62 (2), p.169-175 |
| issn | 0955-3002 1362-3095 |
| language | eng |
| recordid | cdi_informahealthcare_journals_10_1080_09553009214551981 |
| source | MEDLINE; Taylor & Francis:Master (3349 titles); Taylor & Francis Medical Library - CRKN |
| subjects | Adaptation, Physiological - physiology Animals Biological and medical sciences Biological effects of radiation Biology Blastocyst - physiology Blastocyst - radiation effects Fundamental and applied biological sciences. Psychology Ionizing radiations Life Sciences & Biomedicine Life Sciences & Biomedicine - Other Topics Mice Mice, Inbred Strains Nuclear Science & Technology Radiation Tolerance - physiology Radiology, Nuclear Medicine & Medical Imaging Science & Technology Space life sciences Technology Tissues, organs and organisms biophysics |
| title | Adaptive Response in Mouse Embryos? |
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