A Comparison of the Intracellular Uptake and Radiosensitization Efficiency in Different Media of Uncharged 2-nitroimidazoles of Varying Lipophilicity

Summary The effect of varying octanol: water partition coefficients, P, (range 0·026-260) on the uptake of uncharged 2-nitroimidazoles into Chinese hamster V79 379A cells has been studied. Average intracellular concentrations were measured by high performance liquid chromatography after centrifuging...

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Veröffentlicht in:	International journal of radiation biology 1987, Vol.52 (3), p.359-370
Hauptverfasser:	Watts, M.E., Dennis, M.F., Jones, N.R., Stratford, M.R.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cricetinae In Vitro Techniques Nitroimidazoles - metabolism Radiation-Sensitizing Agents - metabolism
Online-Zugang:	Volltext
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