GPIIb-IIIa antagonists cause rapid disaggregation of platelets pre-treated with cytochalasin D. Evidence that the stability of platelet aggregates depends on normal cytoskeletal assembly

Platelet activation is accompanied by changes in the composition of the platelet cytoskeleton with rapid incorporation and displacement of certain proteins. Here we have inhibited cytoskeletal assembly by pretreating platelets with cytochalasin D (CyD) and investigated the effect on the stability of...

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Veröffentlicht in:	Platelets (Edinburgh) 1998, Vol.9 (3-4), p.227-232
Hauptverfasser:	May, J. A., Ratan, H., Glenn, J. R., Losche, W., Spangenberg, P., Heptinstall, S.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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