Differential effect of FGF and PDGF on cell proliferation and migration in osteoblastic cells

It has been known that growth factors such as fibroblast growth factor (FGF) and platelet-derived growth factor (PDGF) can promote proliferation and migration in a variety of cell types including osteoblastic cells. However, the mechanism underlying their action has not been clearly defined. The pre...

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Veröffentlicht in:	Growth factors (Chur, Switzerland) Switzerland), 2007-01, Vol.25 (2), p.77-86
Hauptverfasser:	Kim, Su Jin, Kim, Su Yung, Kwon, Chae Hwa, Kim, Yong Keun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Cycle Cell Line Cell Movement Cell Proliferation Dose-Response Relationship, Drug ERK Extracellular Signal-Regulated MAP Kinases - metabolism Fibroblast Growth Factors - physiology Growth factor Humans Mice migration Models, Biological osteoblastic cells Osteoblasts - metabolism Phosphorylation PI3K/Akt Platelet-Derived Growth Factor - metabolism Platelet-Derived Growth Factor - physiology proliferation Retinoblastoma Protein - metabolism Signal Transduction src-Family Kinases - metabolism Time Factors Wound Healing
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