Sequencing of the Second Exon of the MHC Class II DQ6 Alleles in Patients with Type 1 Diabetes

The MHC class II molecule DQ6 is strongly associated with protection from type 1 diabetes. A small number of diabetic subjects have been typed as positive for DQ6, but it has been suggested that these individuals may possess a mutant form of the molecule, which is structurally altered in such a way...

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Veröffentlicht in:	Autoimmunity (Chur, Switzerland) Switzerland), 2002, Vol.35 (2), p.155-157
Hauptverfasser:	Rayner, M.L., Kelly, M.A., Mijovic, C.H., Barnett, A.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Alleles Biological and medical sciences Child Diabetes Mellitus, Type 1 - genetics Diabetes. Impaired glucose tolerance Disease Protection Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Exons - genetics Hla-DQ HLA-DQ Antigens - chemistry HLA-DQ Antigens - genetics Humans Medical sciences Mhc Class Ii Sequence Analysis, DNA Type 1 Diabetes
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