PEDIATRIC OSTEOSARCOMA: A 35-Year Experience in Slovenia
The purpose of this study was to review all the children and adolescents treated for osteosarcoma in Slovenia between 1968 and 1997. Seventy-four patients were included in this retrospective study and classified according to the newly devised classification based on clinical and imaging studies. The...
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| Veröffentlicht in: | Pediatric hematology and oncology 2005-06, Vol.22 (4), p.335-343 |
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| container_title | Pediatric hematology and oncology |
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| creator | Kuhelj, Dimitrij Jereb, Berta |
| description | The purpose of this study was to review all the children and adolescents treated for osteosarcoma in Slovenia between 1968 and 1997. Seventy-four patients were included in this retrospective study and classified according to the newly devised classification based on clinical and imaging studies. The overall survival rate is 48%. The stage of the disease and the treatment, including chemotherapy, are the only prognostic factors significantly influencing survival. The survival of patients with osteosarcoma has improved with chemotherapy, but new therapeutic strategies should be found for different stages of disease. The authors' newly devised classification based on clinical and imaging studies proved to be adequate. |
| doi_str_mv | 10.1080/08880010590935257 |
| format | Article |
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The authors' newly devised classification based on clinical and imaging studies proved to be adequate.</description><identifier>ISSN: 0888-0018</identifier><identifier>EISSN: 1521-0669</identifier><identifier>DOI: 10.1080/08880010590935257</identifier><identifier>PMID: 16020121</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Adolescent ; Antineoplastic Agents - therapeutic use ; Child ; Combined Modality Therapy ; Humans ; Neoplasm Staging ; Osteosarcoma - mortality ; Osteosarcoma - pathology ; Osteosarcoma - therapy ; Prognosis ; Retrospective Studies ; Slovenia ; Survival Analysis ; Survival Rate</subject><ispartof>Pediatric hematology and oncology, 2005-06, Vol.22 (4), p.335-343</ispartof><rights>2005 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c404t-e8ad5a6af21d3a31c4bd8cfd6fd6eb9e0b3dff9c3ad2e1fd3916064d76cd2fbc3</citedby><cites>FETCH-LOGICAL-c404t-e8ad5a6af21d3a31c4bd8cfd6fd6eb9e0b3dff9c3ad2e1fd3916064d76cd2fbc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/08880010590935257$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/08880010590935257$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,59647,59753,60436,60542,61221,61256,61402,61437</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16020121$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kuhelj, Dimitrij</creatorcontrib><creatorcontrib>Jereb, Berta</creatorcontrib><title>PEDIATRIC OSTEOSARCOMA: A 35-Year Experience in Slovenia</title><title>Pediatric hematology and oncology</title><addtitle>Pediatr Hematol Oncol</addtitle><description>The purpose of this study was to review all the children and adolescents treated for osteosarcoma in Slovenia between 1968 and 1997. Seventy-four patients were included in this retrospective study and classified according to the newly devised classification based on clinical and imaging studies. The overall survival rate is 48%. The stage of the disease and the treatment, including chemotherapy, are the only prognostic factors significantly influencing survival. The survival of patients with osteosarcoma has improved with chemotherapy, but new therapeutic strategies should be found for different stages of disease. The authors' newly devised classification based on clinical and imaging studies proved to be adequate.</description><subject>Adolescent</subject><subject>Antineoplastic Agents - therapeutic use</subject><subject>Child</subject><subject>Combined Modality Therapy</subject><subject>Humans</subject><subject>Neoplasm Staging</subject><subject>Osteosarcoma - mortality</subject><subject>Osteosarcoma - pathology</subject><subject>Osteosarcoma - therapy</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Slovenia</subject><subject>Survival Analysis</subject><subject>Survival Rate</subject><issn>0888-0018</issn><issn>1521-0669</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMFKAzEQhoMotlYfwIvsydvqJOmmWfWy1KoFpdLWg6eQTSZ0Zbtbk1bt27ulBRFBGJjDfP_P8BFySuGCgoRLkFICUEhSSHnCkt4eadOE0RiESPdJe3OPG0C2yFEIbwDAeI8dkhYVwIAy2ibyeXA7zKbjYT8aTaaD0SQb90dP2VWURTyJX1H7aPC1QF9gZTAqqmhS1h9YFfqYHDhdBjzZ7Q55uRtM-w_x4-h-2M8eY9OF7jJGqW2ihXaMWq45Nd3cSuOsaAbzFCHn1rnUcG0ZUmd52vwmurYnjGUuN7xDzre9C1-_rzAs1bwIBstSV1ivghISeE8ktAHpFjS-DsGjUwtfzLVfKwpqo0v90dVkznblq3yO9iex89MAN1ugqFzt5_qz9qVVS70ua--8rkwRFP-v__pXfIa6XM6M9qje6pWvGnH_fPcNieSH7A</recordid><startdate>20050601</startdate><enddate>20050601</enddate><creator>Kuhelj, Dimitrij</creator><creator>Jereb, Berta</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20050601</creationdate><title>PEDIATRIC OSTEOSARCOMA: A 35-Year Experience in Slovenia</title><author>Kuhelj, Dimitrij ; Jereb, Berta</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c404t-e8ad5a6af21d3a31c4bd8cfd6fd6eb9e0b3dff9c3ad2e1fd3916064d76cd2fbc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adolescent</topic><topic>Antineoplastic Agents - therapeutic use</topic><topic>Child</topic><topic>Combined Modality Therapy</topic><topic>Humans</topic><topic>Neoplasm Staging</topic><topic>Osteosarcoma - mortality</topic><topic>Osteosarcoma - pathology</topic><topic>Osteosarcoma - therapy</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Slovenia</topic><topic>Survival Analysis</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kuhelj, Dimitrij</creatorcontrib><creatorcontrib>Jereb, Berta</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric hematology and oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kuhelj, Dimitrij</au><au>Jereb, Berta</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>PEDIATRIC OSTEOSARCOMA: A 35-Year Experience in Slovenia</atitle><jtitle>Pediatric hematology and oncology</jtitle><addtitle>Pediatr Hematol Oncol</addtitle><date>2005-06-01</date><risdate>2005</risdate><volume>22</volume><issue>4</issue><spage>335</spage><epage>343</epage><pages>335-343</pages><issn>0888-0018</issn><eissn>1521-0669</eissn><abstract>The purpose of this study was to review all the children and adolescents treated for osteosarcoma in Slovenia between 1968 and 1997. 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| ispartof | Pediatric hematology and oncology, 2005-06, Vol.22 (4), p.335-343 |
| issn | 0888-0018 1521-0669 |
| language | eng |
| recordid | cdi_informahealthcare_journals_10_1080_08880010590935257 |
| source | MEDLINE; Taylor & Francis:Master (3349 titles); Taylor & Francis Medical Library - CRKN |
| subjects | Adolescent Antineoplastic Agents - therapeutic use Child Combined Modality Therapy Humans Neoplasm Staging Osteosarcoma - mortality Osteosarcoma - pathology Osteosarcoma - therapy Prognosis Retrospective Studies Slovenia Survival Analysis Survival Rate |
| title | PEDIATRIC OSTEOSARCOMA: A 35-Year Experience in Slovenia |
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