Near-infrared spectroscopy of the adult human olfactory cortex
Objective Near-infrared spectroscopy (NIRS) is a non-invasive method for investigating activation of the human cortex. The applicability of NIRS to the olfactory cortex was investigated. Material and Methods The relative oxy- and deoxy-hemoglobin levels of the orbito-frontal cortex during olfactory...
Gespeichert in:
| Veröffentlicht in: | Acta oto-laryngologica 2004-08, Vol.124 (553S), p.95-98 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 98 |
|---|---|
| container_issue | 553S |
| container_start_page | 95 |
| container_title | Acta oto-laryngologica |
| container_volume | 124 |
| creator | Ishimaru, Tadashi Yata, Tsuyoshi Horikawa, Kumiko Hatanaka, Sachiko |
| description | Objective
Near-infrared spectroscopy (NIRS) is a non-invasive method for investigating activation of the human cortex. The applicability of NIRS to the olfactory cortex was investigated.
Material and Methods
The relative oxy- and deoxy-hemoglobin levels of the orbito-frontal cortex during olfactory stimulation in healthy subjects were measured using NIRS.
Results
When perfumed strips containing the odorants β-phenyl ethyl alcohol, iso-valeric acid and γ-undecalactone were presented, the oxy-hemoglobin level increased but the deoxy-hemoglobin level did not change. The increase in the oxy-hemoglobin level was observed bilaterally. A placebo perfumed strip did not elicit a change in the hemoglobin level. It was also observed that the odorant intensity affected the oxy-hemoglobin level. Although the orbito-frontal cortices seemed to be activated bilaterally during olfaction, the right cortex was activated to a greater extent than the left.
Conclusion
NIRS appears to be an adequate method for investigating the human olfactory cortex. |
| doi_str_mv | 10.1080/03655230410017751 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_informahealthcare_journals_10_1080_03655230410017751</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>66745197</sourcerecordid><originalsourceid>FETCH-LOGICAL-c468t-6a902dd2dcd1fd387493c492add8febc44ebbc88a45941e22044cd2478e364b03</originalsourceid><addsrcrecordid>eNp9kM1KxDAURoMozjj6AG6kK3fVJE3aFEWQwT8YdKPrkCYp7ZA2NUnRvr0ZZkBEmFW44Xwf9x4AzhG8QpDBa5jllOIMEgQhKgqKDsAc5RSlGFN0COYwfqc5YeUMnHi_3owlo8dghiguCkjoHNy9auHStq-dcFolftAyOOulHabE1klodCLUaELSjJ3oE2tqIYN1UyKtC_r7FBzVwnh9tnsX4OPx4X35nK7enl6W96tUkpyFNBclxEphJRWqVcYKUmaSlFgoxWpdSUJ0VUnGBKElQRpjSIhUmBRMZzmpYLYAl9vewdnPUfvAu9ZLbYzotR09z_OCUFQWEURbUMYrvNM1H1zbCTdxBPlGGv8nLWYuduVj1Wn1m9hZisDtFoierOvEl3VG8SAmY10U18vW82xf_82feKOFCY2Mwvnajq6P4vZs9wOYWIxD</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>66745197</pqid></control><display><type>article</type><title>Near-infrared spectroscopy of the adult human olfactory cortex</title><source>MEDLINE</source><source>Taylor & Francis Medical Library - CRKN</source><source>Taylor & Francis Journals Complete</source><creator>Ishimaru, Tadashi ; Yata, Tsuyoshi ; Horikawa, Kumiko ; Hatanaka, Sachiko</creator><creatorcontrib>Ishimaru, Tadashi ; Yata, Tsuyoshi ; Horikawa, Kumiko ; Hatanaka, Sachiko</creatorcontrib><description>Objective
Near-infrared spectroscopy (NIRS) is a non-invasive method for investigating activation of the human cortex. The applicability of NIRS to the olfactory cortex was investigated.
Material and Methods
The relative oxy- and deoxy-hemoglobin levels of the orbito-frontal cortex during olfactory stimulation in healthy subjects were measured using NIRS.
Results
When perfumed strips containing the odorants β-phenyl ethyl alcohol, iso-valeric acid and γ-undecalactone were presented, the oxy-hemoglobin level increased but the deoxy-hemoglobin level did not change. The increase in the oxy-hemoglobin level was observed bilaterally. A placebo perfumed strip did not elicit a change in the hemoglobin level. It was also observed that the odorant intensity affected the oxy-hemoglobin level. Although the orbito-frontal cortices seemed to be activated bilaterally during olfaction, the right cortex was activated to a greater extent than the left.
Conclusion
NIRS appears to be an adequate method for investigating the human olfactory cortex.</description><identifier>ISSN: 0001-6489</identifier><identifier>ISSN: 0365-5237</identifier><identifier>EISSN: 1651-2251</identifier><identifier>DOI: 10.1080/03655230410017751</identifier><identifier>PMID: 15277045</identifier><language>eng</language><publisher>Norway: Informa UK Ltd</publisher><subject>Adult ; Aged ; Cerebrovascular Circulation - physiology ; deoxy-hemoglobin ; Female ; Hemoglobins - analysis ; Humans ; iso-valeric acid ; Male ; Middle Aged ; Odorants ; olfaction ; olfactometry ; Olfactory Pathways - physiology ; orbito-frontal cortex ; oxy-hemoglobin ; Oxyhemoglobins - analysis ; Sensitivity and Specificity ; smell ; Spectroscopy, Near-Infrared ; T&T ; β-phenyl ethyl alcohol ; γ-undecalactone</subject><ispartof>Acta oto-laryngologica, 2004-08, Vol.124 (553S), p.95-98</ispartof><rights>2004 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c468t-6a902dd2dcd1fd387493c492add8febc44ebbc88a45941e22044cd2478e364b03</citedby><cites>FETCH-LOGICAL-c468t-6a902dd2dcd1fd387493c492add8febc44ebbc88a45941e22044cd2478e364b03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/03655230410017751$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/03655230410017751$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,59620,59726,60409,60515,61194,61229,61375,61410</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15277045$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ishimaru, Tadashi</creatorcontrib><creatorcontrib>Yata, Tsuyoshi</creatorcontrib><creatorcontrib>Horikawa, Kumiko</creatorcontrib><creatorcontrib>Hatanaka, Sachiko</creatorcontrib><title>Near-infrared spectroscopy of the adult human olfactory cortex</title><title>Acta oto-laryngologica</title><addtitle>Acta Otolaryngol Suppl</addtitle><description>Objective
Near-infrared spectroscopy (NIRS) is a non-invasive method for investigating activation of the human cortex. The applicability of NIRS to the olfactory cortex was investigated.
Material and Methods
The relative oxy- and deoxy-hemoglobin levels of the orbito-frontal cortex during olfactory stimulation in healthy subjects were measured using NIRS.
Results
When perfumed strips containing the odorants β-phenyl ethyl alcohol, iso-valeric acid and γ-undecalactone were presented, the oxy-hemoglobin level increased but the deoxy-hemoglobin level did not change. The increase in the oxy-hemoglobin level was observed bilaterally. A placebo perfumed strip did not elicit a change in the hemoglobin level. It was also observed that the odorant intensity affected the oxy-hemoglobin level. Although the orbito-frontal cortices seemed to be activated bilaterally during olfaction, the right cortex was activated to a greater extent than the left.
Conclusion
NIRS appears to be an adequate method for investigating the human olfactory cortex.</description><subject>Adult</subject><subject>Aged</subject><subject>Cerebrovascular Circulation - physiology</subject><subject>deoxy-hemoglobin</subject><subject>Female</subject><subject>Hemoglobins - analysis</subject><subject>Humans</subject><subject>iso-valeric acid</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Odorants</subject><subject>olfaction</subject><subject>olfactometry</subject><subject>Olfactory Pathways - physiology</subject><subject>orbito-frontal cortex</subject><subject>oxy-hemoglobin</subject><subject>Oxyhemoglobins - analysis</subject><subject>Sensitivity and Specificity</subject><subject>smell</subject><subject>Spectroscopy, Near-Infrared</subject><subject>T&T</subject><subject>β-phenyl ethyl alcohol</subject><subject>γ-undecalactone</subject><issn>0001-6489</issn><issn>0365-5237</issn><issn>1651-2251</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1KxDAURoMozjj6AG6kK3fVJE3aFEWQwT8YdKPrkCYp7ZA2NUnRvr0ZZkBEmFW44Xwf9x4AzhG8QpDBa5jllOIMEgQhKgqKDsAc5RSlGFN0COYwfqc5YeUMnHi_3owlo8dghiguCkjoHNy9auHStq-dcFolftAyOOulHabE1klodCLUaELSjJ3oE2tqIYN1UyKtC_r7FBzVwnh9tnsX4OPx4X35nK7enl6W96tUkpyFNBclxEphJRWqVcYKUmaSlFgoxWpdSUJ0VUnGBKElQRpjSIhUmBRMZzmpYLYAl9vewdnPUfvAu9ZLbYzotR09z_OCUFQWEURbUMYrvNM1H1zbCTdxBPlGGv8nLWYuduVj1Wn1m9hZisDtFoierOvEl3VG8SAmY10U18vW82xf_82feKOFCY2Mwvnajq6P4vZs9wOYWIxD</recordid><startdate>200408</startdate><enddate>200408</enddate><creator>Ishimaru, Tadashi</creator><creator>Yata, Tsuyoshi</creator><creator>Horikawa, Kumiko</creator><creator>Hatanaka, Sachiko</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>200408</creationdate><title>Near-infrared spectroscopy of the adult human olfactory cortex</title><author>Ishimaru, Tadashi ; Yata, Tsuyoshi ; Horikawa, Kumiko ; Hatanaka, Sachiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c468t-6a902dd2dcd1fd387493c492add8febc44ebbc88a45941e22044cd2478e364b03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Cerebrovascular Circulation - physiology</topic><topic>deoxy-hemoglobin</topic><topic>Female</topic><topic>Hemoglobins - analysis</topic><topic>Humans</topic><topic>iso-valeric acid</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Odorants</topic><topic>olfaction</topic><topic>olfactometry</topic><topic>Olfactory Pathways - physiology</topic><topic>orbito-frontal cortex</topic><topic>oxy-hemoglobin</topic><topic>Oxyhemoglobins - analysis</topic><topic>Sensitivity and Specificity</topic><topic>smell</topic><topic>Spectroscopy, Near-Infrared</topic><topic>T&T</topic><topic>β-phenyl ethyl alcohol</topic><topic>γ-undecalactone</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ishimaru, Tadashi</creatorcontrib><creatorcontrib>Yata, Tsuyoshi</creatorcontrib><creatorcontrib>Horikawa, Kumiko</creatorcontrib><creatorcontrib>Hatanaka, Sachiko</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>Acta oto-laryngologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ishimaru, Tadashi</au><au>Yata, Tsuyoshi</au><au>Horikawa, Kumiko</au><au>Hatanaka, Sachiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Near-infrared spectroscopy of the adult human olfactory cortex</atitle><jtitle>Acta oto-laryngologica</jtitle><addtitle>Acta Otolaryngol Suppl</addtitle><date>2004-08</date><risdate>2004</risdate><volume>124</volume><issue>553S</issue><spage>95</spage><epage>98</epage><pages>95-98</pages><issn>0001-6489</issn><issn>0365-5237</issn><eissn>1651-2251</eissn><abstract>Objective
Near-infrared spectroscopy (NIRS) is a non-invasive method for investigating activation of the human cortex. The applicability of NIRS to the olfactory cortex was investigated.
Material and Methods
The relative oxy- and deoxy-hemoglobin levels of the orbito-frontal cortex during olfactory stimulation in healthy subjects were measured using NIRS.
Results
When perfumed strips containing the odorants β-phenyl ethyl alcohol, iso-valeric acid and γ-undecalactone were presented, the oxy-hemoglobin level increased but the deoxy-hemoglobin level did not change. The increase in the oxy-hemoglobin level was observed bilaterally. A placebo perfumed strip did not elicit a change in the hemoglobin level. It was also observed that the odorant intensity affected the oxy-hemoglobin level. Although the orbito-frontal cortices seemed to be activated bilaterally during olfaction, the right cortex was activated to a greater extent than the left.
Conclusion
NIRS appears to be an adequate method for investigating the human olfactory cortex.</abstract><cop>Norway</cop><pub>Informa UK Ltd</pub><pmid>15277045</pmid><doi>10.1080/03655230410017751</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0001-6489 |
| ispartof | Acta oto-laryngologica, 2004-08, Vol.124 (553S), p.95-98 |
| issn | 0001-6489 0365-5237 1651-2251 |
| language | eng |
| recordid | cdi_informahealthcare_journals_10_1080_03655230410017751 |
| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
| subjects | Adult Aged Cerebrovascular Circulation - physiology deoxy-hemoglobin Female Hemoglobins - analysis Humans iso-valeric acid Male Middle Aged Odorants olfaction olfactometry Olfactory Pathways - physiology orbito-frontal cortex oxy-hemoglobin Oxyhemoglobins - analysis Sensitivity and Specificity smell Spectroscopy, Near-Infrared T&T β-phenyl ethyl alcohol γ-undecalactone |
| title | Near-infrared spectroscopy of the adult human olfactory cortex |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-16T03%3A14%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Near-infrared%20spectroscopy%20of%20the%20adult%20human%20olfactory%20cortex&rft.jtitle=Acta%20oto-laryngologica&rft.au=Ishimaru,%20Tadashi&rft.date=2004-08&rft.volume=124&rft.issue=553S&rft.spage=95&rft.epage=98&rft.pages=95-98&rft.issn=0001-6489&rft.eissn=1651-2251&rft_id=info:doi/10.1080/03655230410017751&rft_dat=%3Cproquest_pubme%3E66745197%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=66745197&rft_id=info:pmid/15277045&rfr_iscdi=true |