Eudragit® microparticles as a possible tool for ophthalmic administration of acyclovir

This paper describes the production and characterization of polyacrylic polymer (Eudragit® RL, RS and NE) microparticles by spray drying method. Microparticles were designed for ophthalmic administration of acyclovir. Microparticle morphology was characterized by optical and electron microscopy. The...

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Veröffentlicht in:	Journal of microencapsulation 2007-01, Vol.24 (5), p.445-456
Hauptverfasser:	Cortesi, Rita, Lahm Ajanji, Sara C., Sivieri, Elisa, Manservigi, Marco, Fundueanu, Gheorghe, Menegatti, Enea, Esposito, Elisabetta
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyclovir Acyclovir - administration & dosage Acyclovir - pharmacology Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Antiviral Agents - administration & dosage Antiviral Agents - pharmacology Biological and medical sciences Cercopithecus aethiops Delayed-Action Preparations Dose-Response Relationship, Drug Drug Carriers Drug Compounding - methods Drug Delivery Systems Eudragit General pharmacology herpes simplex virus Herpesvirus 1, Human - drug effects Herpesvirus 1, Human - growth & development Humans Medical sciences Microscopy, Electron, Scanning Microspheres ocular delivery Ophthalmic Solutions Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Polymers Polymethacrylic Acids Vero Cells Virus Replication - drug effects
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