DEET-loaded solid lipid particles for skin delivery: In vitro release and skin permeation characteristics in different vehicles

DEET (N,N-diethyl m-toluamide) is a lipophilic compound which has a common use as an insect repellent and causes not only skin irritation but also systemic side effects at high concentrations in long-term skin application. In this study, DEET is incorporated into solid lipid particles, a colloidal d...

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Veröffentlicht in:Journal of microencapsulation 2006-05, Vol.23 (3), p.315-327
Hauptverfasser: Iscan, Y., Hekimoglu, S., Sargon, M. F., Hincal, A. A.
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Sprache:eng
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