BREATH CONDENSATE LEVELS OF 8-ISOPROSTANE AND LEUKOTRIENE B4 AFTER OZONE INHALATION ARE GREATER IN SENSITIVE VERSUS NONSENSITIVE SUBJECTS

Ozone (O3) inhalation induces pulmonary function decrements and inflammation. The present study was designed to determine if a relationship exists between O3 induced pulmonary function changes and the presence of inflammatory markers as measured in exhaled breath condensates (EBCs) obtained from O3-...

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Veröffentlicht in:	Experimental lung research 2007-04, Vol.33 (3-4), p.115-133
Hauptverfasser:	Alfaro, Mario F., Walby, William F., Adams, William C., Schelegle, Edward S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Air Pollutants - adverse effects arachidonic acid metabolites Biomarkers - analysis Breath Tests Dinoprost - analogs & derivatives Dinoprost - analysis exhaled breath condensate Female Forced Expiratory Volume - drug effects Humans individual sensitivity Inhalation Exposure Leukotriene B4 - analysis Lung Diseases - chemically induced Lung Diseases - physiopathology Male Nitrates - analysis Nitrites - analysis ozone Ozone - adverse effects Respiratory Mechanics - drug effects Tidal Volume - drug effects Time Factors Vital Capacity - drug effects
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