ALTERED DRUG RESISTANCE AND RECOVERY FROM PARALYSIS IN DROSOPHILA MELANOGASTER WITH A DEFICIENT HISTAMINE-GATED CHLORIDE CHANNEL

The recent identification and characterization of two genes, encoding histamine-gated chloride channel subunits from Drosophila melanogaster , has confirmed that histamine is a major neurotransmitter in the fruitfly. One of the cloned genes, hclA (synonyms: HisCl - &#102 1 ; HisCl2 ), correspond...

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Veröffentlicht in:	Journal of neurogenetics 2002-10, Vol.16 (4), p.249-261
Hauptverfasser:	IOVCHEV, MLADEN, KODROV, PLAMEN, WOLSTENHOLME, ADRIAN J., PAK, WILLIAM L., SEMENOV, EUGENE P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics, Inhalation - pharmacology Animals Chloride Channels - genetics Chloride Channels - physiology Drosophila melanogaster - drug effects Drosophila melanogaster - genetics Drosophila melanogaster - physiology Drug Resistance Ether - pharmacology Female Histamine - physiology Ion Channel Gating - physiology Ivermectin - analogs & derivatives Ivermectin - pharmacology Male Mutation ort Phenotype
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