A Study of Tamm-Horsfall Protein Excretion in Hypertensive Patients and Type 1 Diabetic Patients

Objective: The study was performed in order to evaluate to what extent hypertension or diabetes mellitus may affect the urinary excretion rate of Tamm-Horsfall protein. Materials and methods: The urinary excretion rates of albumin and Tamm-Horsfall protein, a measure of glomerular and distal tubular...

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Veröffentlicht in:Scandinavian journal of urology and nephrology 1999, Vol.33 (3), p.187-191
1. Verfasser: Ole Torffvit, Carl-David Agardh, Thomas Thulin
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description Objective: The study was performed in order to evaluate to what extent hypertension or diabetes mellitus may affect the urinary excretion rate of Tamm-Horsfall protein. Materials and methods: The urinary excretion rates of albumin and Tamm-Horsfall protein, a measure of glomerular and distal tubular function, respectively were measured in patients with essential hypertension (n = 17) and in type 1 diabetes with (n = 20) or without nephropathy (n = 8) and in apparently healthy subjects (n = 10). Results: Mean 24-h ambulatory blood pressure measurements showed higher blood pressure levels in the hypertensive (167/106 mmHg, p
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Materials and methods: The urinary excretion rates of albumin and Tamm-Horsfall protein, a measure of glomerular and distal tubular function, respectively were measured in patients with essential hypertension (n = 17) and in type 1 diabetes with (n = 20) or without nephropathy (n = 8) and in apparently healthy subjects (n = 10). Results: Mean 24-h ambulatory blood pressure measurements showed higher blood pressure levels in the hypertensive (167/106 mmHg, p</description><subject>Aged</subject><subject>Albuminuria - physiopathology</subject><subject>Albuminuria - urine</subject><subject>Analysis of Variance</subject><subject>Annan klinisk medicin</subject><subject>Arterial hypertension. Arterial hypotension</subject><subject>Associated diseases and complications</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Blood Pressure</subject><subject>Cardiology. Vascular system</subject><subject>Chronic Disease</subject><subject>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</subject><subject>Clinical Medicine</subject><subject>Creatinine - analysis</subject><subject>Diabetes Mellitus, Type 1 - complications</subject><subject>Diabetes Mellitus, Type 1 - physiopathology</subject><subject>Diabetes Mellitus, Type 1 - urine</subject><subject>Diabetes. Impaired glucose tolerance</subject><subject>Diabetic Nephropathies - physiopathology</subject><subject>Diabetic Nephropathies - urine</subject><subject>diabetic nephropathy</subject><subject>Endocrine pancreas. 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Arterial hypotension</topic><topic>Associated diseases and complications</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Blood Pressure</topic><topic>Cardiology. Vascular system</topic><topic>Chronic Disease</topic><topic>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</topic><topic>Clinical Medicine</topic><topic>Creatinine - analysis</topic><topic>Diabetes Mellitus, Type 1 - complications</topic><topic>Diabetes Mellitus, Type 1 - physiopathology</topic><topic>Diabetes Mellitus, Type 1 - urine</topic><topic>Diabetes. Impaired glucose tolerance</topic><topic>Diabetic Nephropathies - physiopathology</topic><topic>Diabetic Nephropathies - urine</topic><topic>diabetic nephropathy</topic><topic>Endocrine pancreas. Apud cells (diseases)</topic><topic>Endocrinology and Diabetes</topic><topic>Endocrinopathies</topic><topic>Endokrinologi och diabetes</topic><topic>Female</topic><topic>Humans</topic><topic>hypertension</topic><topic>Hypertension - complications</topic><topic>Hypertension - physiopathology</topic><topic>Hypertension - urine</topic><topic>Klinisk medicin</topic><topic>Male</topic><topic>Medical and Health Sciences</topic><topic>Medical sciences</topic><topic>Medicin och hälsovetenskap</topic><topic>Middle Aged</topic><topic>Mucoproteins - urine</topic><topic>Other Clinical Medicine</topic><topic>Tamm-Horsfall protein</topic><topic>tubular function</topic><topic>type 1 diabetes</topic><topic>urinary albumin</topic><topic>Uromodulin</topic><toplevel>online_resources</toplevel><creatorcontrib>Ole Torffvit, Carl-David Agardh, Thomas Thulin</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Lunds universitet</collection><jtitle>Scandinavian journal of urology and nephrology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ole Torffvit, Carl-David Agardh, Thomas Thulin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Study of Tamm-Horsfall Protein Excretion in Hypertensive Patients and Type 1 Diabetic Patients</atitle><jtitle>Scandinavian journal of urology and nephrology</jtitle><addtitle>Scand J Urol Nephrol</addtitle><date>1999</date><risdate>1999</risdate><volume>33</volume><issue>3</issue><spage>187</spage><epage>191</epage><pages>187-191</pages><issn>0036-5599</issn><eissn>1651-2065</eissn><coden>SJUNAS</coden><abstract>Objective: The study was performed in order to evaluate to what extent hypertension or diabetes mellitus may affect the urinary excretion rate of Tamm-Horsfall protein. Materials and methods: The urinary excretion rates of albumin and Tamm-Horsfall protein, a measure of glomerular and distal tubular function, respectively were measured in patients with essential hypertension (n = 17) and in type 1 diabetes with (n = 20) or without nephropathy (n = 8) and in apparently healthy subjects (n = 10). Results: Mean 24-h ambulatory blood pressure measurements showed higher blood pressure levels in the hypertensive (167/106 mmHg, p</abstract><cop>Basingstoke</cop><pub>Informa UK Ltd</pub><pmid>10452295</pmid><doi>10.1080/003655999750015970</doi><tpages>5</tpages></addata></record>
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identifier ISSN: 0036-5599
ispartof Scandinavian journal of urology and nephrology, 1999, Vol.33 (3), p.187-191
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source MEDLINE; Taylor & Francis:Master (3349 titles); Taylor & Francis Medical Library - CRKN
subjects Aged
Albuminuria - physiopathology
Albuminuria - urine
Analysis of Variance
Annan klinisk medicin
Arterial hypertension. Arterial hypotension
Associated diseases and complications
Biological and medical sciences
Blood and lymphatic vessels
Blood Pressure
Cardiology. Vascular system
Chronic Disease
Clinical manifestations. Epidemiology. Investigative techniques. Etiology
Clinical Medicine
Creatinine - analysis
Diabetes Mellitus, Type 1 - complications
Diabetes Mellitus, Type 1 - physiopathology
Diabetes Mellitus, Type 1 - urine
Diabetes. Impaired glucose tolerance
Diabetic Nephropathies - physiopathology
Diabetic Nephropathies - urine
diabetic nephropathy
Endocrine pancreas. Apud cells (diseases)
Endocrinology and Diabetes
Endocrinopathies
Endokrinologi och diabetes
Female
Humans
hypertension
Hypertension - complications
Hypertension - physiopathology
Hypertension - urine
Klinisk medicin
Male
Medical and Health Sciences
Medical sciences
Medicin och hälsovetenskap
Middle Aged
Mucoproteins - urine
Other Clinical Medicine
Tamm-Horsfall protein
tubular function
type 1 diabetes
urinary albumin
Uromodulin
title A Study of Tamm-Horsfall Protein Excretion in Hypertensive Patients and Type 1 Diabetic Patients
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