A Study of Tamm-Horsfall Protein Excretion in Hypertensive Patients and Type 1 Diabetic Patients

Objective: The study was performed in order to evaluate to what extent hypertension or diabetes mellitus may affect the urinary excretion rate of Tamm-Horsfall protein. Materials and methods: The urinary excretion rates of albumin and Tamm-Horsfall protein, a measure of glomerular and distal tubular...

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Veröffentlicht in:	Scandinavian journal of urology and nephrology 1999, Vol.33 (3), p.187-191
1. Verfasser:	Ole Torffvit, Carl-David Agardh, Thomas Thulin
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Albuminuria - physiopathology Albuminuria - urine Analysis of Variance Annan klinisk medicin Arterial hypertension. Arterial hypotension Associated diseases and complications Biological and medical sciences Blood and lymphatic vessels Blood Pressure Cardiology. Vascular system Chronic Disease Clinical manifestations. Epidemiology. Investigative techniques. Etiology Clinical Medicine Creatinine - analysis Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - physiopathology Diabetes Mellitus, Type 1 - urine Diabetes. Impaired glucose tolerance Diabetic Nephropathies - physiopathology Diabetic Nephropathies - urine diabetic nephropathy Endocrine pancreas. Apud cells (diseases) Endocrinology and Diabetes Endocrinopathies Endokrinologi och diabetes Female Humans hypertension Hypertension - complications Hypertension - physiopathology Hypertension - urine Klinisk medicin Male Medical and Health Sciences Medical sciences Medicin och hälsovetenskap Middle Aged Mucoproteins - urine Other Clinical Medicine Tamm-Horsfall protein tubular function type 1 diabetes urinary albumin Uromodulin
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Zusammenfassung:	Objective: The study was performed in order to evaluate to what extent hypertension or diabetes mellitus may affect the urinary excretion rate of Tamm-Horsfall protein. Materials and methods: The urinary excretion rates of albumin and Tamm-Horsfall protein, a measure of glomerular and distal tubular function, respectively were measured in patients with essential hypertension (n = 17) and in type 1 diabetes with (n = 20) or without nephropathy (n = 8) and in apparently healthy subjects (n = 10). Results: Mean 24-h ambulatory blood pressure measurements showed higher blood pressure levels in the hypertensive (167/106 mmHg, p
ISSN:	0036-5599 1651-2065
DOI:	10.1080/003655999750015970