DIFFERENCES BETWEEN LIPOPOLYSACCHARIDE AND DOUBLE-STRANDED RNA IN INNATE IMMUNE RESPONSES OF BV2 MICROGLIAL CELLS

Microglial cells are thought to be major inflammatory cells in the central nervous system; however, sufficient information about the effects of double-stranded RNA (dsRNA) in microglial cells is lacking. The present study compared the innate immune responses of the murine microglial cell line BV2 to...

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Veröffentlicht in:	International journal of neuroscience 2007-07, Vol.117 (7), p.885-894
Hauptverfasser:	JAE LEE, HEE, KONG, PIL-JAE, LEE, SANG-HYUN, KWON, OH-YOON, CHUN, WAN-JOO, KIM, SUNG-SOO
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals BV2 microglia, double-stranded RNA Cell Line Cyclooxygenase 2 - genetics Cyclooxygenase 2 - metabolism Gene Expression Regulation - immunology IL-1β Immunity, Innate - immunology Immunity, Innate - physiology Inflammation Mediators - metabolism innate immune system Interleukin 1 Receptor Antagonist Protein - genetics Interleukin 1 Receptor Antagonist Protein - metabolism Interleukin-1beta - genetics Interleukin-1beta - metabolism Interleukin-6 - genetics Interleukin-6 - metabolism lipopolysaccharide Lipopolysaccharides - immunology Mice Microglia - immunology Poly I-C - immunology pro-inflammation RNA, Double-Stranded - immunology RNA, Messenger - analysis Signal Transduction Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - metabolism
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