Spiral ligament fibrocytes release chemokines in response to otitis media pathogens

Conclusion. Spiral ligament fibrocytes (SLFs) may be involved in the innate immune response of the inner ear by producing chemoattractants for recruiting inflammatory cells such as neutrophils and monocytes. Objective. The purpose of this study was to investigate the cellular responses of SLFs when...

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Veröffentlicht in:	Acta oto-laryngologica 2006-06, Vol.126 (6), p.564-569
Hauptverfasser:	Moon, Sung-Kyun, Park, Raekil, Lee, Haa-Yung, Nam, Gyu-June, Cha, Kiweon, Andalibi, Ali, Lim, David J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Line, Transformed Chemokine CCL2 - genetics Chemokine CCL2 - metabolism Chemokines - genetics Chemokines - metabolism cytokine-induced neutrophil chemoattractant Fibroblasts - immunology Gene Expression - physiology Haemophilus Infections - immunology Haemophilus influenzae Haemophilus influenzae - immunology Humans Immunity, Innate - immunology Inflammation Mediators - metabolism interleukin-1 Interleukin-1 - physiology Medical sciences monocyte chemotactic protein Monocytes - immunology Neutrophil Infiltration - immunology Nontypable Haemophilus influenzae Organ of Corti - immunology otitis media Otitis Media - immunology Otorhinolaryngology. Stomatology Pneumococcal Infections - immunology Polymerase Chain Reaction Protein Array Analysis Rats RNA, Messenger - genetics Spiral Ganglion - immunology Spiral Lamina - immunology Streptococcus pneumoniae
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