Prediction of Drug-Induced Arrhythmogenic Risk Using In Silico Populations of Models

In silico tools hold potential to improve drug cardiotoxicity predictions. However, computational models do not usually consider inter-individual variability, which may be crucial when predicting rare adverse events such as drug-induced Torsade de Pointes (TdP). In this study we analyze the effect o...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Llopis-Lorente, Jordi, Trenor, Beatriz, Saiz, Javier
Format:	Tagungsbericht
Sprache:	eng
Schlagworte:	Biological system modeling Computational modeling Drugs Simulation Sociology Support vector machines Training
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!