In vivo droplet vaporization using diagnostic ultrasound-a potential method for occlusion therapy?
The experimental objective was to determine whether a transpulmonary droplet emulsion (90%30 /spl mu/m) which would be utilized to occlude the capillary bed of tissue. Gas bubbles can be made in vivo to potentially block capillaries, by acoustic droplet vaporization (ADV) of injected, superheated, d...
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| creator | Kripfgans, O.D. Fowlkes, J.B. Eldevik, O.P. Carson, P.L. Woydt, M. |
| description | The experimental objective was to determine whether a transpulmonary droplet emulsion (90%30 /spl mu/m) which would be utilized to occlude the capillary bed of tissue. Gas bubbles can be made in vivo to potentially block capillaries, by acoustic droplet vaporization (ADV) of injected, superheated, dodecafluoropentane droplets. Droplets evaporate into gas bubbles when exposed to an acoustic field who's peak rarefactional pressure exceeds a well defined threshold. It has been found that I.A. as well as I.V. injections can be used to introduce the emulsion into the blood stream and subsequently perform ADV (using B- and M-mode on a clinical ultrasound scanner) at the target site. I.V. administration results in a lower gas bubble yield, possibly due to droplet filtering in the lung, dilution in the blood volume or other circulatory effects. |
| doi_str_mv | 10.1109/ULTSYM.2000.921596 |
| format | Conference Proceeding |
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I.V. administration results in a lower gas bubble yield, possibly due to droplet filtering in the lung, dilution in the blood volume or other circulatory effects.</description><identifier>ISSN: 1051-0117</identifier><identifier>ISBN: 9780780363656</identifier><identifier>ISBN: 0780363655</identifier><identifier>DOI: 10.1109/ULTSYM.2000.921596</identifier><language>eng</language><publisher>IEEE</publisher><subject>Acoustic fields ; Acoustic pulses ; Acoustic transducers ; Blood ; Bubbles (in fluids) ; Cancer ; Emulsions ; Focusing ; Frequency ; In vivo ; Medical imaging ; Medical treatment ; Neoplasms ; Scanning ; Tissue ; Ultrasonic devices ; Ultrasonic imaging ; Vaporization</subject><ispartof>2000 IEEE Ultrasonics Symposium. Proceedings. An International Symposium (Cat. 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An International Symposium (Cat. No.00CH37121)</title><addtitle>ULTSYM</addtitle><description>The experimental objective was to determine whether a transpulmonary droplet emulsion (90%<6 /spl mu/m diameter) can be used to temporarily form large gas bubbles (>30 /spl mu/m) which would be utilized to occlude the capillary bed of tissue. Gas bubbles can be made in vivo to potentially block capillaries, by acoustic droplet vaporization (ADV) of injected, superheated, dodecafluoropentane droplets. Droplets evaporate into gas bubbles when exposed to an acoustic field who's peak rarefactional pressure exceeds a well defined threshold. It has been found that I.A. as well as I.V. injections can be used to introduce the emulsion into the blood stream and subsequently perform ADV (using B- and M-mode on a clinical ultrasound scanner) at the target site. I.V. administration results in a lower gas bubble yield, possibly due to droplet filtering in the lung, dilution in the blood volume or other circulatory effects.</description><subject>Acoustic fields</subject><subject>Acoustic pulses</subject><subject>Acoustic transducers</subject><subject>Blood</subject><subject>Bubbles (in fluids)</subject><subject>Cancer</subject><subject>Emulsions</subject><subject>Focusing</subject><subject>Frequency</subject><subject>In vivo</subject><subject>Medical imaging</subject><subject>Medical treatment</subject><subject>Neoplasms</subject><subject>Scanning</subject><subject>Tissue</subject><subject>Ultrasonic devices</subject><subject>Ultrasonic imaging</subject><subject>Vaporization</subject><issn>1051-0117</issn><isbn>9780780363656</isbn><isbn>0780363655</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2000</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><sourceid>RIE</sourceid><recordid>eNotkL1OwzAYRS0BEqX0BTp5Ykv5_BMnnhBC_FQqYqAdmCLH-dIapXGwnUrl6alUpCvd5Zw7XELmDBaMgb7frNafX-8LDgALzVmu1QWZ6aKEU4QSKleXZMIgZxkwVlyTmxi_ATjkXE5IvezpwR08bYIfOkz0YAYf3K9Jzvd0jK7f0saZbe9jcpaOXQom-rFvMkMHn7BPznR0j2nnG9r6QL213Uk7yWmHwQzHh1ty1Zou4uy_p2Tz8rx-estWH6_Lp8dV5jiIlGkwCo21vFVlKRtQOUqhLBRtzevSal7n3GqhJJONbK2oNZdtgSgNKJ1LJqbk7rw7BP8zYkzV3kWLXWd69GOsOJOKM1aewPkZdIhYDcHtTThW5-vEH6u_ZMg</recordid><startdate>2000</startdate><enddate>2000</enddate><creator>Kripfgans, O.D.</creator><creator>Fowlkes, J.B.</creator><creator>Eldevik, O.P.</creator><creator>Carson, P.L.</creator><creator>Woydt, M.</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope></search><sort><creationdate>2000</creationdate><title>In vivo droplet vaporization using diagnostic ultrasound-a potential method for occlusion therapy?</title><author>Kripfgans, O.D. ; Fowlkes, J.B. ; Eldevik, O.P. ; Carson, P.L. ; Woydt, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i203t-90a6eacc2f6884d065e436c07fb2b8c92b52c936414d4fc3b924f7ee4a0695413</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Acoustic fields</topic><topic>Acoustic pulses</topic><topic>Acoustic transducers</topic><topic>Blood</topic><topic>Bubbles (in fluids)</topic><topic>Cancer</topic><topic>Emulsions</topic><topic>Focusing</topic><topic>Frequency</topic><topic>In vivo</topic><topic>Medical imaging</topic><topic>Medical treatment</topic><topic>Neoplasms</topic><topic>Scanning</topic><topic>Tissue</topic><topic>Ultrasonic devices</topic><topic>Ultrasonic imaging</topic><topic>Vaporization</topic><toplevel>online_resources</toplevel><creatorcontrib>Kripfgans, O.D.</creatorcontrib><creatorcontrib>Fowlkes, J.B.</creatorcontrib><creatorcontrib>Eldevik, O.P.</creatorcontrib><creatorcontrib>Carson, P.L.</creatorcontrib><creatorcontrib>Woydt, M.</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Kripfgans, O.D.</au><au>Fowlkes, J.B.</au><au>Eldevik, O.P.</au><au>Carson, P.L.</au><au>Woydt, M.</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>In vivo droplet vaporization using diagnostic ultrasound-a potential method for occlusion therapy?</atitle><btitle>2000 IEEE Ultrasonics Symposium. Proceedings. An International Symposium (Cat. No.00CH37121)</btitle><stitle>ULTSYM</stitle><date>2000</date><risdate>2000</risdate><volume>2</volume><spage>1449</spage><epage>1452 vol.2</epage><pages>1449-1452 vol.2</pages><issn>1051-0117</issn><isbn>9780780363656</isbn><isbn>0780363655</isbn><abstract>The experimental objective was to determine whether a transpulmonary droplet emulsion (90%<6 /spl mu/m diameter) can be used to temporarily form large gas bubbles (>30 /spl mu/m) which would be utilized to occlude the capillary bed of tissue. Gas bubbles can be made in vivo to potentially block capillaries, by acoustic droplet vaporization (ADV) of injected, superheated, dodecafluoropentane droplets. Droplets evaporate into gas bubbles when exposed to an acoustic field who's peak rarefactional pressure exceeds a well defined threshold. It has been found that I.A. as well as I.V. injections can be used to introduce the emulsion into the blood stream and subsequently perform ADV (using B- and M-mode on a clinical ultrasound scanner) at the target site. I.V. administration results in a lower gas bubble yield, possibly due to droplet filtering in the lung, dilution in the blood volume or other circulatory effects.</abstract><pub>IEEE</pub><doi>10.1109/ULTSYM.2000.921596</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | ISSN: 1051-0117 |
| ispartof | 2000 IEEE Ultrasonics Symposium. Proceedings. An International Symposium (Cat. No.00CH37121), 2000, Vol.2, p.1449-1452 vol.2 |
| issn | 1051-0117 |
| language | eng |
| recordid | cdi_ieee_primary_921596 |
| source | IEEE Electronic Library (IEL) Conference Proceedings |
| subjects | Acoustic fields Acoustic pulses Acoustic transducers Blood Bubbles (in fluids) Cancer Emulsions Focusing Frequency In vivo Medical imaging Medical treatment Neoplasms Scanning Tissue Ultrasonic devices Ultrasonic imaging Vaporization |
| title | In vivo droplet vaporization using diagnostic ultrasound-a potential method for occlusion therapy? |
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