Novel Detection Scheme for X-Ray Small-Angle Scattering
X-ray imaging techniques, including X-ray radiography and computed tomography, have been in use for decades and proven effective and indispensable in diagnosis and therapy due to their fine resolution and fast acquisition speed. However, the innate disadvantage of X-ray is the poor soft tissue contr...
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| Veröffentlicht in: | IEEE transactions on radiation and plasma medical sciences 2018-07, Vol.2 (4), p.315-325 |
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| creator | Li, Guang Cong, Wenxiang Michaelson, James S. Liu, Hong Gjesteby, Lars Wang, Ge |
| description | X-ray imaging techniques, including X-ray radiography and computed tomography, have been in use for decades and proven effective and indispensable in diagnosis and therapy due to their fine resolution and fast acquisition speed. However, the innate disadvantage of X-ray is the poor soft tissue contrast. Small-angle scattering signals were shown to provide unique information about the abnormality of soft tissues that is complementary to the traditional attenuation image. Currently, there is no effective small-angle scattering detection system. In this paper, we propose a new "collimation" design dedicated to capture a small-angle scattering radiographic image directly, which carries critical pathological information for differentiation between normal and abnormal tissues. Our design consists of two interlaced gratings so that both primary flux and Compton scattering photons are effectively blocked to leave the apertures mainly open to small-angle scattering photons. Theoretical analysis and Monte Carlo simulations demonstrate that small-angle scattering radiography is feasible with our proposed technology. |
| doi_str_mv | 10.1109/TRPMS.2018.2839066 |
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However, the innate disadvantage of X-ray is the poor soft tissue contrast. Small-angle scattering signals were shown to provide unique information about the abnormality of soft tissues that is complementary to the traditional attenuation image. Currently, there is no effective small-angle scattering detection system. In this paper, we propose a new "collimation" design dedicated to capture a small-angle scattering radiographic image directly, which carries critical pathological information for differentiation between normal and abnormal tissues. Our design consists of two interlaced gratings so that both primary flux and Compton scattering photons are effectively blocked to leave the apertures mainly open to small-angle scattering photons. 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(IEEE) 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c450t-f42e3f8ce1cd75280d299076087fb8200c59bfc98d62dcc183e91e3f82b611a43</citedby><cites>FETCH-LOGICAL-c450t-f42e3f8ce1cd75280d299076087fb8200c59bfc98d62dcc183e91e3f82b611a43</cites><orcidid>0000-0003-4306-6395 ; 0000-0002-5021-7705 ; 0000-0003-2908-1759 ; 0000-0002-0896-8409 ; 0000-0002-2656-7705 ; 0000-0003-4606-2568</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/8361486$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>230,315,781,785,797,886,27929,27930,54763</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/8361486$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30854499$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Guang</creatorcontrib><creatorcontrib>Cong, Wenxiang</creatorcontrib><creatorcontrib>Michaelson, James S.</creatorcontrib><creatorcontrib>Liu, Hong</creatorcontrib><creatorcontrib>Gjesteby, Lars</creatorcontrib><creatorcontrib>Wang, Ge</creatorcontrib><title>Novel Detection Scheme for X-Ray Small-Angle Scattering</title><title>IEEE transactions on radiation and plasma medical sciences</title><addtitle>TRPMS</addtitle><addtitle>IEEE Trans Radiat Plasma Med Sci</addtitle><description>X-ray imaging techniques, including X-ray radiography and computed tomography, have been in use for decades and proven effective and indispensable in diagnosis and therapy due to their fine resolution and fast acquisition speed. 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| subjects | Apertures Attenuation Collimation Computed tomography Computer simulation Detectors Elastic scattering Geometry Grating-based X-ray imaging Gratings Image detection Imaging Imaging techniques Medical imaging pathological studies Photonics Photons Radiography Scattering small-angle scattering Soft tissues Theoretical analysis Tissues X ray imagery X-ray imaging X-ray radiography X-rays |
| title | Novel Detection Scheme for X-Ray Small-Angle Scattering |
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