Ventricular diastolic impedance Z(t): validation of a new, model-based image processing derived index of global diastolic function
The quest for a noninvasive, global index of left ventricular (LV) diastolic function has not yet been attained. Current echocardiographic methods extract components of diastolic function from selected aspects of transmitral flow velocity, ventricular geometry and wall motion. Diastolic left ventric...
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| creator | Milde, J.M. Sessoms, M.W. Lisauskas, J.B. Courtois, M. Singh, J. Kovacs, S.J. |
| description | The quest for a noninvasive, global index of left ventricular (LV) diastolic function has not yet been attained. Current echocardiographic methods extract components of diastolic function from selected aspects of transmitral flow velocity, ventricular geometry and wall motion. Diastolic left ventricular pressure P(t) and transmitral flow Q(t) define global diastolic impedance as Z(t)=P(t)/Q(t). Since P(t) requires cardiac catherization, we expressed P(t) via the nonsteady Bernoulli equation using Doppler echocardiographically measurable transmitral flow velocity v(t) and acceleration v=dv/dt. For validation we compared catheterization (invasively) derived Z/sub inv/(t) with echo (noninvasively) derived Z/sub noninv/(t) and found excellent agreement. We conclude that the echocardiographically determined LV diastolic impedance Z/sub noninv/(t) provides a physiologically sound quantitative index of global LV diastolic function. |
| doi_str_mv | 10.1109/IEMBS.1999.802286 |
| format | Conference Proceeding |
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Current echocardiographic methods extract components of diastolic function from selected aspects of transmitral flow velocity, ventricular geometry and wall motion. Diastolic left ventricular pressure P(t) and transmitral flow Q(t) define global diastolic impedance as Z(t)=P(t)/Q(t). Since P(t) requires cardiac catherization, we expressed P(t) via the nonsteady Bernoulli equation using Doppler echocardiographically measurable transmitral flow velocity v(t) and acceleration v=dv/dt. For validation we compared catheterization (invasively) derived Z/sub inv/(t) with echo (noninvasively) derived Z/sub noninv/(t) and found excellent agreement. 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Current echocardiographic methods extract components of diastolic function from selected aspects of transmitral flow velocity, ventricular geometry and wall motion. Diastolic left ventricular pressure P(t) and transmitral flow Q(t) define global diastolic impedance as Z(t)=P(t)/Q(t). Since P(t) requires cardiac catherization, we expressed P(t) via the nonsteady Bernoulli equation using Doppler echocardiographically measurable transmitral flow velocity v(t) and acceleration v=dv/dt. For validation we compared catheterization (invasively) derived Z/sub inv/(t) with echo (noninvasively) derived Z/sub noninv/(t) and found excellent agreement. We conclude that the echocardiographically determined LV diastolic impedance Z/sub noninv/(t) provides a physiologically sound quantitative index of global LV diastolic function.</description><subject>Acceleration</subject><subject>Biophysics</subject><subject>Cardiology</subject><subject>Catheterization</subject><subject>Electrocardiography</subject><subject>Equations</subject><subject>Equations of motion</subject><subject>Filling</subject><subject>Graphics</subject><subject>Hemodynamics</subject><subject>Image color analysis</subject><subject>Image processing</subject><subject>Impedance</subject><subject>Mathematical models</subject><issn>1094-687X</issn><issn>0589-1019</issn><issn>1558-4615</issn><isbn>0780356748</isbn><isbn>9780780356740</isbn><isbn>9780780356757</isbn><isbn>0780356756</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>1999</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><sourceid>RIE</sourceid><recordid>eNpNULtOwzAUtXhI0MIHwOQJgUSK7cSOzQZVgUpFDFQIsUSOfVMZuU6JkwIrX06qMjDd4bzuOQidUDKilKir6eTx9nlElVIjSRiTYgcdUs5lkgnKd9GA5JKkXOSZ3OsBorJEyPz1AA1ifCeEEcLpIfp5gdA2znReN9g6HdvaO4PdcgVWBwP47by9uMZr7Z3VrasDriuscYDPS7ysLfik1BFsL9ALwKumNhCjCwtsoXHrDRAsfG1EC1-X2v_LqLpgNo5HaL_SPsLx3x2i-d1kPn5IZk_30_HNLHGUyjZhJc8NsSVhWuWcG5qrEoiWUOYKcqsFMSChSo3JOCelohZEJbgRVapkpdMhOtva9k9-dBDbYumiAe91gLqLBaMZk4yTnni6JToAKFZNX635LrYTp7_S7HDh</recordid><startdate>1999</startdate><enddate>1999</enddate><creator>Milde, J.M.</creator><creator>Sessoms, M.W.</creator><creator>Lisauskas, J.B.</creator><creator>Courtois, M.</creator><creator>Singh, J.</creator><creator>Kovacs, S.J.</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope></search><sort><creationdate>1999</creationdate><title>Ventricular diastolic impedance Z(t): validation of a new, model-based image processing derived index of global diastolic function</title><author>Milde, J.M. ; Sessoms, M.W. ; Lisauskas, J.B. ; Courtois, M. ; Singh, J. ; Kovacs, S.J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i118t-2b57c0db02a9755c179be0a8eb79e7da60ce8ef3cc4550b91de6f65c6f398fa3</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Acceleration</topic><topic>Biophysics</topic><topic>Cardiology</topic><topic>Catheterization</topic><topic>Electrocardiography</topic><topic>Equations</topic><topic>Equations of motion</topic><topic>Filling</topic><topic>Graphics</topic><topic>Hemodynamics</topic><topic>Image color analysis</topic><topic>Image processing</topic><topic>Impedance</topic><topic>Mathematical models</topic><toplevel>online_resources</toplevel><creatorcontrib>Milde, J.M.</creatorcontrib><creatorcontrib>Sessoms, M.W.</creatorcontrib><creatorcontrib>Lisauskas, J.B.</creatorcontrib><creatorcontrib>Courtois, M.</creatorcontrib><creatorcontrib>Singh, J.</creatorcontrib><creatorcontrib>Kovacs, S.J.</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Milde, J.M.</au><au>Sessoms, M.W.</au><au>Lisauskas, J.B.</au><au>Courtois, M.</au><au>Singh, J.</au><au>Kovacs, S.J.</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Ventricular diastolic impedance Z(t): validation of a new, model-based image processing derived index of global diastolic function</atitle><btitle>Proceedings of the First Joint BMES/EMBS Conference : serving humanity advancing technology, Oct. 13-16, 99, Atlanta, GA, USA</btitle><stitle>IEMBS</stitle><date>1999</date><risdate>1999</risdate><volume>1</volume><spage>234 vol.1</spage><epage>234</epage><pages>234 vol.1-234</pages><issn>1094-687X</issn><issn>0589-1019</issn><eissn>1558-4615</eissn><isbn>0780356748</isbn><isbn>9780780356740</isbn><isbn>9780780356757</isbn><isbn>0780356756</isbn><abstract>The quest for a noninvasive, global index of left ventricular (LV) diastolic function has not yet been attained. Current echocardiographic methods extract components of diastolic function from selected aspects of transmitral flow velocity, ventricular geometry and wall motion. Diastolic left ventricular pressure P(t) and transmitral flow Q(t) define global diastolic impedance as Z(t)=P(t)/Q(t). Since P(t) requires cardiac catherization, we expressed P(t) via the nonsteady Bernoulli equation using Doppler echocardiographically measurable transmitral flow velocity v(t) and acceleration v=dv/dt. For validation we compared catheterization (invasively) derived Z/sub inv/(t) with echo (noninvasively) derived Z/sub noninv/(t) and found excellent agreement. We conclude that the echocardiographically determined LV diastolic impedance Z/sub noninv/(t) provides a physiologically sound quantitative index of global LV diastolic function.</abstract><pub>IEEE</pub><doi>10.1109/IEMBS.1999.802286</doi><tpages>1</tpages></addata></record> |
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| ispartof | Proceedings of the First Joint BMES/EMBS Conference : serving humanity advancing technology, Oct. 13-16, 99, Atlanta, GA, USA, 1999, Vol.1, p.234 vol.1-234 |
| issn | 1094-687X 0589-1019 1558-4615 |
| language | eng |
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| source | IEEE Electronic Library (IEL) Conference Proceedings |
| subjects | Acceleration Biophysics Cardiology Catheterization Electrocardiography Equations Equations of motion Filling Graphics Hemodynamics Image color analysis Image processing Impedance Mathematical models |
| title | Ventricular diastolic impedance Z(t): validation of a new, model-based image processing derived index of global diastolic function |
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