The effect of alternative diastolic pressure-volume relations on transmitral Doppler flow: comparison by model-based image processing

The effect of alternative diastolic pressure-volume relations on transmitral Doppler flow: comparison by model-based image processing

Several mathematical expressions (linear, exponential, logarithmic) have been used to fit the measured diastolic pressure-volume (P-V) relation. We determined whether the different P-V relations could be distinguished by analysis of in-vivo physiologic data. Transmitral Doppler E-waves of 15 subject...

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Hauptverfasser: Lisauskas, J.B., Kovacs, S.J.
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Biophysics
Cardiology
Damping
Doppler effect
Filling
Image processing
Image restoration
Mathematical model
Mathematical models
Oscillators
Predictive models
Pressure measurement
Springs
Volume measurement
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description Several mathematical expressions (linear, exponential, logarithmic) have been used to fit the measured diastolic pressure-volume (P-V) relation. We determined whether the different P-V relations could be distinguished by analysis of in-vivo physiologic data. Transmitral Doppler E-waves of 15 subjects were analyzed using model-based image processing (MBIP). One dimensional linear, logarithmic, and exponential force displacement equivalents of the P-V relation were used in our lumped-parameter kinematic model of transmitral flow for MBIP. Minimized least-square best fits of model predicted to observed Doppler E-wave flow velocity were similar regardless of choice of mathematical expression. We conclude that application of the simplest P-V relation is justified in MBIP analysis of transmitral Doppler flow.
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subjects Biophysics
Cardiology
Damping
Doppler effect
Filling
Image processing
Image restoration
Mathematical model
Mathematical models
Oscillators
Predictive models
Pressure measurement
Springs
Volume measurement
title The effect of alternative diastolic pressure-volume relations on transmitral Doppler flow: comparison by model-based image processing
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