The effect of bioenergetic impairment of cytosolic processes in spatio-temporal Ca2+ dynamics in a three-dimensional cardiomyocyte model

The heart consumes large amounts of energy with each beat. Mitochondria are the source of over 95% of this energy in the form of ATP and rely on increased Ca 2 + uptake to stimulate production in times of increased work. Ca 2+ uptake into the mitochondria primarily occurs within microdomains. Struct...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Jones, Gareth M., Henggui Zhang, Colman, Michael A.
Format:	Tagungsbericht
Sprache:	eng
Schlagworte:	Biological system modeling Calcium Computational modeling Hafnium Heart Production Solid modeling
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!