Implantable biosensor telemetry and interface using an optocoupler

This paper details the development of a miniature electronics package for implantable amperometric glucose sensors. The package includes a potentiostat to bias the glucose sensor with the proper excitation voltage, a transimpedance amplifier to develop voltage level data from sensor current, and an optocoupler device to interface to a commercially available telemetry unit which then transmits the glucose concentration data to a receiver and data collection computer. Instrumentation described in this paper will allow other researchers to easily develop a miniaturized implantable potentiostat/telemetry unit for their own sensor applications.