On-chip base sequencing using a two-stage reaction-control scheme: 3.6-times-faster and 1/100-reduced-data-volume ISFET-based DNA sequencer
A novel two-stage reaction-control scheme with a background-cancelling circuit - for reducing data volume and analysis time of an ion-sensitive-FET (ISFET) - based DNA sequencer-is proposed. The scheme successfully reduces the background noise and renders time-consuming background analysis unnecessa...
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| creator | Yanagawa, Y. Itabashi, N. Migitaka, S. Yokoi, T. Yoshida, M. Kawahara, T. |
| description | A novel two-stage reaction-control scheme with a background-cancelling circuit - for reducing data volume and analysis time of an ion-sensitive-FET (ISFET) - based DNA sequencer-is proposed. The scheme successfully reduces the background noise and renders time-consuming background analysis unnecessary. It also reduces sample-to-data time by 72% (3.6 times faster) and data volume by two orders of magnitude. |
| doi_str_mv | 10.1109/BioCAS.2013.6679668 |
| format | Conference Proceeding |
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| ispartof | 2013 IEEE Biomedical Circuits and Systems Conference (BioCAS), 2013, p.178-181 |
| issn | 2163-4025 2766-4465 |
| language | eng |
| recordid | cdi_ieee_primary_6679668 |
| source | IEEE Electronic Library (IEL) Conference Proceedings |
| subjects | Arrays DNA DNA sequencer Heating Ion-sensitive FET on-chip base-sequencing Polymers Sequential analysis System-on-chip Transistors |
| title | On-chip base sequencing using a two-stage reaction-control scheme: 3.6-times-faster and 1/100-reduced-data-volume ISFET-based DNA sequencer |
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